Life course variation in the relation between maternal marital status and preterm birth.

Life course variation in the relation between maternal marital status and preterm birth.
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DOI:
10.1016/j.annepidem.2012.01.002
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发表时间:
2012-03
影响因子:
5.6
通讯作者:
Galea, Sandro
Galea, Sandro
中科院分区:
医学3区
文献类型:
--
作者:
El-Sayed, Abdulrahman M.;Tracy, Melissa;Galea, Sandro

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孕产妇婚姻对早产(PTB)有保护作用,而高龄产妇则与PTB风险增加有关。由于社会因素与健康之间的关系可能在整个生命过程中发生变化,我们评估了婚姻状况与PTB风险之间的关系如何随着母亲年龄的变化而变化。我们评估了1995-2006年间密歇根州所有活产单胎婴儿中婚姻状况和母亲年龄作为PTB决定因素之间的相互作用。我们还根据种族拟合了分层模型。我们计算了每个年龄组中预测PTB的绝对差异,以及婚姻状况对PTB的优势比。在调整后的模型中,婚姻状况与母亲年龄之间存在显著的交互作用(p <0.001)。在20-25岁的母亲中,婚姻状况对PTB的预测概率有轻微差异(绝对差异为1.5%);这一差异在31岁后显著增加(3.9%或更高)。肺结核的发病率也有类似的趋势。黑人母亲和白人母亲的调查结果相似。婚姻与PTB之间的关系可能随母亲年龄的变化而变化,这表明社会因素对不良分娩结局风险的影响可能因母亲的生活轨迹而异。我们讨论了对这些发现的合理解释。
Maternal marriage is protective against preterm birth (PTB), while advanced maternal age is associated with increased PTB risk. As relations between social factors and health may vary over the life course, we assessed how the relation between marital status and PTB risk may change with maternal age. We assessed the interaction between marital status and maternal age as a determinant of PTB among all live singleton births in Michigan between 1995-2006. We also fit stratified models by race. We calculated absolute differences in predicted PTB as well as odds ratios of PTB by marital status for each age group. In adjusted models, there was a significant interaction (pinteraction<0.001) between marital status and maternal age. The predicted probability of PTB by marital status was marginally different among mothers aged 20-25 years (absolute difference of 1.5%); this difference was substantially higher (3.9% or higher) after 31 years of age. Odds of PTB followed a similar trajectory. Findings were similar among Black and White mothers. The relationship between marriage and PTB may vary with maternal age suggesting that the influence of social factors on risk for adverse birth outcomes may differ through the maternal life trajectory. We discuss plausible explanations for these findings.
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发表时间: 1996-03-01
期刊: SCANDINAVIAN JOURNAL OF SOCIAL MEDICINE
影响因子: --
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