Feast or famine: the host-pathogen battle over amino acids.
Feast or famine: the host-pathogen battle over amino acids.
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DOI:
10.1111/cmi.12140
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发表时间:
2013-07
影响因子:
3.4
通讯作者:
Rubin EJ
中科院分区:
文献类型:
--
作者:
Zhang YJ;Rubin EJ
Intracellular bacterial pathogens often rely on their hosts for essential nutrients. Host cells, in turn, attempt to limit nutrient availability, using starvation as a mechanism of innate immunity. Here we discuss both host mechanisms of amino acid starvation and the diverse adaptations of pathogens to their nutrient-deprived environments. These processes provide both key insights into immune subversion and new targets for drug development.
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影响因子:
17.1
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Fabri M;Stenger S;Shin DM;Yuk JM;Liu PT;Realegeno S;Lee HM;Krutzik SR;Schenk M;Sieling PA;Teles R;Montoya D;Iyer SS;Bruns H;Lewinsohn DM;Hollis BW;Hewison M;Adams JS;Steinmeyer A;Zügel U;Cheng G;Jo EK;Bloom BR;Modlin RL
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DOI:
10.1073/pnas.1631248100
发表时间:
2003-08-19
影响因子:
11.1
作者:
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通讯作者:
Barry, CE
影响因子:
4.8
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影响因子:
3.2
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