A dose-response perspective on college drinking and related problems.

A dose-response perspective on college drinking and related problems.
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DOI:
10.1111/j.1360-0443.2009.02767.x
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发表时间:
2010-02
期刊:
Addiction (Abingdon, England)
影响因子:
--
通讯作者:
Lascala EA
Lascala EA
中科院分区:
其他
文献类型:
--
作者:
Gruenewald PJ;Johnson FW;Ponicki WR;Lascala EA

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为了考察大量饮酒对大学生饮酒者问题风险的具体贡献程度,本文开发并测试了一个酒精使用的剂量-反应模型,该模型将饮酒特定数量的频率与饮酒问题的发生率联系起来。一个数学模型被开发出来,该模型使用美国加利福尼亚州14所大学的8,698名大学生饮酒者的自我报告数据,估计饮酒量和饮酒问题之间的剂量-反应关系。该模型假设饮酒风险是每天饮酒量和饮酒天数相加的直接单调函数。饮酒问题会随着饮酒场合的不同而累积,也是大学饮酒者报告饮酒问题的累积报告的基础。使用该模型进行的统计分析表明,饮酒问题与每种饮酒水平有关,但在饮酒三次时增加5倍,之后逐渐增加。问题与饮用三杯饮料的场合关系最大,超过一半的报告问题与饮用四杯或更少饮料的场合有关。在男性和女性之间,以及不同的“轻度”、“中度”和“重度”饮酒者之间,有一些重要的剂量反应差异。大学生中的许多问题都与饮酒量相对较少(2-4杯)有关。减少大学饮酒问题的计划应该强调与低饮酒水平相关的风险。
In order to examine the degree to which heavy drinking specifically contributes to risks for problems among college drinkers this paper develops and tests a dose-response model of alcohol use that relates frequencies of drinking specific quantities of alcohol to the incidence of drinking problems. A mathematical model was developed that enabled estimation of dose-response relationships between drinking quantities and drinking problems using self-report data from 8,698 college drinkers across 14 campuses in California, USA. The model assumes that drinking risks are a direct monotone function of the amount consumed per day and additive across drinking days. Drinking problems accumulate across drinking occasions and are the basis for cumulative reports of drinking problems reported by college drinkers. Statistical analyses using the model showed that drinking problems were related to every drinking level, but increased 5-fold at three drinks and more gradually thereafter. Problems were most strongly associated with occasions on which three drinks were consumed, and over half of all reported problems were related to occasions on which 4 or fewer drinks were consumed. There were some important differences in dose-responsiveness between men and women and between different groups of “light,” “moderate,” and “heavier” drinkers. Many problems among college students are associated with drinking relatively small amounts of alcohol (2 – 4 drinks). Programs to reduce college drinking problems should emphasize risks associated with low drinking levels.
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发表时间: 2003-07-01
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影响因子: --
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