A mouse model of breast cancer metastasis to the choroid of the eye.
A mouse model of breast cancer metastasis to the choroid of the eye.
复制标题
乳腺癌转移至眼睛脉络膜的小鼠模型。
DOI：
10.1007/s10585-006-9012-3
复制
发表时间：
2005
影响因子：
4
通讯作者：
Rittling,SusanR
中科院分区：
文献类型：
--
作者：
Kuhn,Misty;Shah,Sarah;Natasha,Tajneen;Rittling,SusanR
Transformed mouse mammary epithelial cells, r3T, injected into the arterial circulation form bone metastases with high frequency. Here we report that metastases to the choroid of the eye also occur in these mice with a penetrance of at least 50%. The tumors can occupy as much as half the volume of the eye, and pigmented cells become incorporated into and distributed throughout the tumors. Pigmentation is also observed in the brains and optic nerves of mice with choroidal tumors, suggesting that the tumor cells stimulate migration of pigmented cells along the optic nerve into the brain. To our knowledge, this is the first mouse model of breast cancer choroidal metastasis, and should be useful in the study of this disease.
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玉米中的突变活性：其在个体发育中的激活时间
影响因子：
56.9
作者：
D. Robertson
通讯作者：
D. Robertson
玉米4个控制元件系统突变体活性及其与Mu突变体相互作用的测试
DOI：
10.1016/0027-5107(81)90198-6
发表时间：
1981
期刊：
Mutation Research
影响因子：
--
作者：
D. Robertson;P. Mascia
通讯作者：
P. Mascia
玉米的稳定非突变株具有与 Mu1 转座元件同源的序列。
影响因子：
3.3
作者：
Chandler,V;Rivin,C;Walbot,V
通讯作者：
Walbot,V
遗传学、发育和进化
DOI：
--
发表时间：
1986
期刊：
Stadler Genetics Symposia Series
影响因子：
--
作者：
J. P. Gustafson;G. Stebbins;F. Ayala
通讯作者：
F. Ayala
非洲爪蟾染色体和扩增核糖体 DNA 的组成和结构。
影响因子：
5.6
作者：
I. Dawid;D. D. Brown;R. Reeder
通讯作者：
R. Reeder