Stable non-mutator stocks of maize have sequences homologous to the Mu1 transposable element.

Stable non-mutator stocks of maize have sequences homologous to the Mu1 transposable element.
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玉米的稳定非突变株具有与 Mu1 转座元件同源的序列。

DOI:
10.1093/genetics/114.3.1007
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发表时间:
1986
期刊:
影响因子:
3.3
通讯作者:
Walbot,V
Walbot,V
中科院分区:
生物学2区
文献类型:
--
作者:
Chandler,V;Rivin,C;Walbot,V

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Mutator stocks of maize produce mutants at many loci at rates 20- to 50-fold above spontaneous levels. Current evidence suggests that this high mutation rate is mediated by an active transposable element system,Mu. Members of this transposable element family are found in ~10-60 copies in Mutator stocks. We report here an initial characterization of previously undetected sequences homologous toMuelements in eight non-Mutator inbred lines and varieties of maize that have a normal low mutation rate. All stocks have ~40 copies of sequences homologous only to the terminal repeat and show weak homology to an internal probe. In addition, several of the stocks contain an intactMuelement. One intactMuelement and two terminal-specific clones have been isolated from one non-Mutator line, B37. The cloned sequences have been used to demonstrate that in genomic DNA the intact element, termedMu1.4B37, is modified, such that restriction sites in its termini are not accessible to cleavage by theHinfI restriction enzyme. This modification is similar to that observed in Mutator lines that have lost activity. We hypothesize that the DNA modification of theMu-like element may contribute to the lack of Mutator activity in B37.
DOI: 10.1016/0092-8674(82)90463-9
发表时间: 1982-01-01
期刊: CELL
影响因子: 64.5
作者:
BINGHAM, PM;KIDWELL, MG;RUBIN, GM
通讯作者: RUBIN, GM
DOI: --
发表时间: 1977-08
期刊: Genetics
影响因子: 3.3
作者:
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DOI: --
发表时间: 1984
期刊: Nature
影响因子: 64.8
作者:
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通讯作者: S. Cotter
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DOI: 10.1002/j.1460-2075.1985.tb03671.x
发表时间: 1985
期刊: The EMBO Journal
影响因子: --
作者:
Z. Schwarz‐Sommer;A. Gierl;H. Cuypers;Peter A. Peterson;H. Saedler
通讯作者: H. Saedler
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DOI: 10.1016/0076-6879(79)68021-7
发表时间: 1979
影响因子: --
作者:
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