Effect of nanoparticles on protein folding and fibrillogenesis.

Effect of nanoparticles on protein folding and fibrillogenesis.
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纳米颗粒对蛋白质折叠和纤维形成的影响

DOI:
10.3390/ijms10020646
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发表时间:
2009-02
影响因子:
5.6
通讯作者:
Perrett S
Perrett S
中科院分区:
生物学2区
文献类型:
--
作者:
Fei L;Perrett S

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The large surface area and small size of nanoparticles provide properties and applications that are distinct from those of bulk materials. The ability of nanoparticles to influence protein folding and aggregation is interesting, not only because of the potential beneficial applications, but also the potential risks to human health and the environment. This makes it essential that we understand the effect of nanoparticles on fundamental biological process, like protein folding. Here, we review studies that have examined the effect of nanoparticles on protein folding and aggregation, providing insight both into the mechanisms of these processes and how they may be controlled.
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