Adherence of Candida species to host tissues and plastic surfaces.
Adherence of Candida species to host tissues and plastic surfaces.
复制标题
念珠菌物种对宿主组织和塑料表面的粘附。
DOI:
10.1093/clinids/8.1.73
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发表时间:
1986
期刊:
影响因子:
--
通讯作者:
EdwardsJr,JE
中科院分区:
文献类型:
--
作者:
Rotrosen,D;Calderone,RA;EdwardsJr,JE
Adherence ofCandidaspecies to host tissues and nonbiologic materials has been studied in vivo and in vitro. Attachment ofCandida albicansto mucosal cells, fibrin-platelet matrices, vascular endothelial cells, and plastic materials has been examined to elucidate early events in the pathogenesis of mucosal colonization and infection, candidal endocarditis, tissue invasion from the intravascular space, and infection of prosthetic devices. Adherence ofC. albicansandCandida tropicalisexceeds that of less virulentCandidaspecies, and germinatedC. albicanscells adhere to host tissues more readily than do yeast-phase organisms. The adhesin ofCandidathat mediates attachment has yet to be characterized at the molecular level; however, on the basis of competitive inhibition by crude and purified cell wall products, blocking by antibody and lectin, and controlled degradation of the cell surface ofCandida, it appears that mannans and mannoproteins are important constituents of the adhesin. The methods currently used to assay adherence ofCandidaall have limitations, and an approach to resolving these limitations is one of several areas that warrant further investigation.
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影响因子:
20.3
作者:
T. Lane;G. Lamkin
通讯作者:
G. Lamkin
DOI:
--
发表时间:
1985
期刊:
American journal of hematology/oncology
影响因子:
--
作者:
G. Rodgers;C. Noguchi;A. Schechter
通讯作者:
A. Schechter
影响因子:
20.3
作者:
O. Linderkamp;H. Meiselman
通讯作者:
O. Linderkamp;H. Meiselman
影响因子:
20.3
作者:
R. Kahn;R. Allen;J. Baldassare
通讯作者:
J. Baldassare
影响因子:
1.1
作者:
Chien,S;Schmalzer,EA;Lee,MM;Impelluso,T;Skalak,R
通讯作者:
Skalak,R