Development of opioid rapid response system: Protocol for a randomized controlled trial.
Development of opioid rapid response system: Protocol for a randomized controlled trial.
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DOI：
10.1016/j.cct.2022.106727
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发表时间：
2022-04
影响因子：
2.2
通讯作者：
Hecht, Michael
中科院分区：
文献类型：
--
作者：
Jayawardene, Wasantha;Pezalla, Annie;Henderson, Cris;Hecht, Michael
阿片类药物过量需要快速反应，但紧急救援人员到达现场给药纳洛酮的速度有限。如果非专业人员接受纳洛酮管理培训，并被告知服用过量，就可以挽救更多的生命。本研究旨在研究阿片类药物快速反应系统（ORRS）的可行性，该系统可以招募、培训并将社区中过量事件的市民反应者实时联系起来，以管理纳洛酮。本文的目的是提出通过多种通信渠道招募参与者的协议；互动式与异步式在线培训的开发与评估；将外行人员随机分配到在线纳洛酮培训组或候补对照组；在培训前后测量参与者的知识、技能和态度；并向参与者分发鼻内纳洛酮包，以便在他们社区的过量事件中使用。抽样：利用有目的的抽样方法的组合，来自印第安纳州五个县的外行人，他们不认为自己是目前的第一响应者，被邀请参加。设计：在这项双臂随机候补对照研究中（N=220），受试者被分配到在线培训组或候补组，两周后接受培训。分析：将使用线性混合模型来确定训练组目标结果的变化，并适应固定和随机效应。虽然ORRS可以成为社区参与的、具有成本效益的基于技术的阿片类药物过量应急响应模式，但研究方案对于涉及外行人的其他应急响应方案也很有用。
Opioid overdoses require a rapid response, but emergency responders are limited in how quickly they can arrive at the scene for administering naloxone. If laypersons are trained to administer naloxone and are notified of overdoses, more lives can be saved. This study aimed to examine the feasibility of the Opioid Rapid Response System (ORRS) that recruits, trains, and links citizen responders to overdose events in their community in real-time to administer naloxone. Aim of this paper is to present the protocols for recruiting participants through multiple communication channels; developing and evaluating the online training which has both interactive and asynchronous modules; randomly assigning laypersons to either online naloxone training or waitlist control group; measuring participants’ knowledge, skills, and attitudes before and after the training; and distributing intranasal naloxone kits to participants for use in events of overdose in their community. Sampling: Utilizing a combination of purposive sampling methods, laypersons from across five Indiana counties who did not self-identify as current first responders were invited to participate. Design: In this two-arm randomized waitlist-controlled study (N=220), individuals were assigned into either online training or waitlist control that received the training two weeks later. Analysis: A linear mixed model will be used for determining the changes in targeted outcomes in the training group and accommodate for fixed and random effects. While ORRS can become a community-engaged, cost-effective model for technology-based emergency response for opioid overdoses, study protocols can be useful for other emergency response programs that involve laypersons.
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影响因子：
3.7
作者：
Coffin PO;Santos GM;Matheson T;Behar E;Rowe C;Rubin T;Silvis J;Vittinghoff E
通讯作者：
Vittinghoff E
影响因子：
6
作者：
Boslett, Andrew J.;Denham, Alina;Hill, Elaine L.
通讯作者：
Hill, Elaine L.
影响因子：
4.8
作者：
Corace, Kimberly;Garber, Gary
通讯作者：
Garber, Gary
影响因子：
3.9
作者：
Choi, Hye Jeong;Krieger, Janice L.;Hecht, Michael L.
通讯作者：
Hecht, Michael L.
DOI：
10.1023/a:1026016131401
发表时间：
2003-12-01
期刊：
Prevention science : the official journal of the Society for Prevention Research
影响因子：
--
作者：
Hecht, Michael L;Marsiglia, Flavio Francisco;Miller-Day, Michelle
通讯作者：
Miller-Day, Michelle