The size, burden and cost of disorders of the brain in the UK.
The size, burden and cost of disorders of the brain in the UK.
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DOI：
10.1177/0269881113495118
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发表时间：
2013-09
期刊：
影响因子：
--
通讯作者：
Sahakian BJ
中科院分区：
文献类型：
--
作者：
Fineberg NA;Haddad PM;Carpenter L;Gannon B;Sharpe R;Young AH;Joyce E;Rowe J;Wellsted D;Nutt DJ;Sahakian BJ
本文的目的是提高人们对英国精神和神经疾病（脑部疾病）的患病率和费用的认识。英国 18 种脑部疾病的数据是从对欧洲流行病学数据和患病率的系统回顾中提取的，并总结了每种疾病的成本（2010 年值）。英国约有 4500 万例脑部疾病病例，每年造成的损失达 1340 亿欧元。最常见的是头痛、焦虑症、睡眠障碍、情绪障碍和躯体形式障碍。然而，五种最昂贵的疾病（百万欧元）是： 痴呆症：22,164 欧元；精神障碍：16,717欧元；情绪障碍：19,238 欧元；成瘾：11,719 欧元；焦虑症：11,687 欧元。除精神病外，这五种疾病属于每个受试者直接医疗支出最低的疾病（<3000 欧元）。成本的大致细分为：50% 间接成本、25% 直接非医疗成本和 25% 直接医疗保健成本。鉴于人口老龄化，英国脑部疾病的患病率和费用可能会增加。转化神经科学研究有潜力开发更有效的治疗方法，但资金不足。解决脑部疾病带来的临床和经济挑战需要欧盟和国家层面的协调努力，以改变当前的科学、医疗保健和教育议程。
The aim of this paper is to increase awareness of the prevalence and cost of psychiatric and neurological disorders (brain disorders) in the UK. UK data for 18 brain disorders were extracted from a systematic review of European epidemiological data and prevalence rates and the costs of each disorder were summarized (2010 values). There were approximately 45 million cases of brain disorders in the UK, with a cost of €134 billion per annum. The most prevalent were headache, anxiety disorders, sleep disorders, mood disorders and somatoform disorders. However, the five most costly disorders (€ million) were: dementia: €22,164; psychotic disorders: €16,717; mood disorders: €19,238; addiction: €11,719; anxiety disorders: €11,687. Apart from psychosis, these five disorders ranked amongst those with the lowest direct medical expenditure per subject (<€3000). The approximate breakdown of costs was: 50% indirect costs, 25% direct non-medical and 25% direct healthcare costs. The prevalence and cost of UK brain disorders is likely to increase given the ageing population. Translational neurosciences research has the potential to develop more effective treatments but is underfunded. Addressing the clinical and economic challenges posed by brain disorders requires a coordinated effort at an EU and national level to transform the current scientific, healthcare and educational agenda.
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影响因子：
5.1
作者：
Andlin-Sobocki, P;Jönsson, B;Olesen, J
通讯作者：
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影响因子：
5.6
作者：
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通讯作者：
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影响因子：
10
作者：
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通讯作者：
Kjellberg, Jakob
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14
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通讯作者：
Jonsson, Linus
影响因子：
11
作者：
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通讯作者：
Ekbom, A