Real-time, automatic, open-source sleep stage classification system using single EEG for mice.
Real-time, automatic, open-source sleep stage classification system using single EEG for mice.
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DOI:
10.1038/s41598-021-90332-1
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发表时间:
2021-05-27
影响因子:
4.6
通讯作者:
Sakaguchi M
中科院分区:
文献类型:
--
作者:
Tezuka T;Kumar D;Singh S;Koyanagi I;Naoi T;Sakaguchi M
We developed a real-time sleep stage classification system with a convolutional neural network using only a one-channel electro-encephalogram source from mice and universally available features in any time-series data: raw signal, spectrum, and zeitgeber time. To accommodate historical information from each subject, we included a long short-term memory recurrent neural network in combination with the universal features. The resulting system (UTSN-L) achieved 90% overall accuracy and 81% multi-class Matthews Correlation Coefficient, with particularly high-quality judgements for rapid eye movement sleep (91% sensitivity and 98% specificity). This system can enable automatic real-time interventions during rapid eye movement sleep, which has been difficult due to its relatively low abundance and short duration. Further, it eliminates the need for ordinal pre-calibration, electromyogram recording, and manual classification and thus is scalable. The code is open-source with a graphical user interface and closed feedback loop capability, making it easily adaptable to a wide variety of end-user needs. By allowing large-scale, automatic, and real-time sleep stage-specific interventions, this system can aid further investigations of the functions of sleep and the development of new therapeutic strategies for sleep-related disorders.
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影响因子:
3.2
作者:
Bresch E;Großekathöfer U;Garcia-Molina G
通讯作者:
Garcia-Molina G
影响因子:
5.6
作者:
Patanaik A;Ong JL;Gooley JJ;Ancoli-Israel S;Chee MWL
通讯作者:
Chee MWL
DOI:
10.1109/tnsre.2017.2776149
发表时间:
2018-01-01
影响因子:
4.9
作者:
Memar, Pejman;Faradji, Farhad
通讯作者:
Faradji, Farhad
影响因子:
16.2
作者:
GoodSmith D;Chen X;Wang C;Kim SH;Song H;Burgalossi A;Christian KM;Knierim JJ
通讯作者:
Knierim JJ
DOI:
10.1007/bf01722097
发表时间:
1918-01-01
期刊:
PFLUGERS ARCHIV FUR DIE GESAMTE PHYSIOLOGIE DES MENSCHEN UND DER TIERE
影响因子:
--
作者:
Szymamski, JS
通讯作者:
Szymamski, JS