LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse.

LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse.
复制标题

LncRNA2Target v2.0:人类和小鼠lncRNA靶基因的综合数据库

DOI:
10.1093/nar/gky1051
复制
发表时间:
2019-01-08
影响因子:
14.9
通讯作者:
Jiang Q
Jiang Q
中科院分区:
生物学2区
文献类型:
--
作者:
Cheng L;Wang P;Tian R;Wang S;Guo Q;Luo M;Zhou W;Liu G;Jiang H;Jiang Q

文献摘要

参考文献

被引文献

相似文献

摘要长链非编码RNA(lncRNA)在基因表达调控中起着至关重要的作用,越来越多的研究者开始关注lncRNA靶基因的鉴定。然而,没有在线资源库可用于收集由lncRNA调控的靶基因的信息。为了方便研究人员了解感兴趣的lncRNA调控哪些基因,我们在2015年开发了一个名为lncRNA 2 Target的数据库,以提供lncRNA靶基因的全面资源。为了更新今年的数据库,我们从2014年8月1日至2018年4月30日发表的论文中检索了所有新的lncRNA-靶标关系,以及特定lncRNA敲减或过表达前后的RNA-seq数据集。LncRNA 2 Target数据库v2.0提供了一个网络界面,通过该界面,其用户可以搜索特定lncRNA的靶标或靶向特定基因的lncRNA,并且可以在http://123.59.132.21/lncrna2target上免费访问。
Abstract Long non-coding RNAs (lncRNAs) play crucial roles in regulating gene expression, and a growing number of researchers have focused on the identification of target genes of lncRNAs. However, no online repository is available to collect the information on target genes regulated by lncRNAs. To make it convenient for researchers to know what genes are regulated by a lncRNA of interest, we developed a database named lncRNA2Target to provide a comprehensive resource of lncRNA target genes in 2015. To update the database this year, we retrieved all new lncRNA–target relationships from papers published from 1 August 2014 to 30 April 2018 and RNA-seq datasets before and after knockdown or overexpression of a specific lncRNA. LncRNA2Target database v2.0 provides a web interface through which its users can search for the targets of a particular lncRNA or for the lncRNAs that target a particular gene, and is freely accessible at http://123.59.132.21/lncrna2target.
DOI: 10.1093/bioinformatics/btu638
发表时间: 2015-01-15
期刊: Bioinformatics (Oxford, England)
影响因子: --
作者:
Anders S;Pyl PT;Huber W
通讯作者: Huber W
DOI: 10.1093/nar/gkv007
发表时间: 2015-04-20
影响因子: 14.9
作者:
Ritchie ME;Phipson B;Wu D;Hu Y;Law CW;Shi W;Smyth GK
通讯作者: Smyth GK
DOI: 10.1161/atvbaha.114.303240
发表时间: 2014-06
期刊: Arteriosclerosis, thrombosis, and vascular biology
影响因子: --
作者:
Bell RD;Long X;Lin M;Bergmann JH;Nanda V;Cowan SL;Zhou Q;Han Y;Spector DL;Zheng D;Miano JM
通讯作者: Miano JM
使用集成生物医学网络预测疾病相关基因
DOI: 10.1186/s12864-016-3263-4
发表时间: 2017-01-25
期刊: BMC genomics
影响因子: 4.4
作者:
Peng J;Bai K;Shang X;Wang G;Xue H;Jin S;Cheng L;Wang Y;Chen J
通讯作者: Chen J
DOI: 10.1038/nature08975
发表时间: 2010-04-15
期刊: Nature
影响因子: 64.8
作者:
通讯作者: --