HTSeq--a Python framework to work with high-throughput sequencing data.
HTSeq--a Python framework to work with high-throughput sequencing data.
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DOI:
10.1093/bioinformatics/btu638
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发表时间:
2015-01-15
期刊:
影响因子:
--
通讯作者:
Huber W
中科院分区:
文献类型:
--
作者:
Anders S;Pyl PT;Huber W
Motivation: A large choice of tools exists for many standard tasks in the analysis of high-throughput sequencing (HTS) data. However, once a project deviates from standard workflows, custom scripts are needed. Results: We present HTSeq, a Python library to facilitate the rapid development of such scripts. HTSeq offers parsers for many common data formats in HTS projects, as well as classes to represent data, such as genomic coordinates, sequences, sequencing reads, alignments, gene model information and variant calls, and provides data structures that allow for querying via genomic coordinates. We also present htseq-count, a tool developed with HTSeq that preprocesses RNA-Seq data for differential expression analysis by counting the overlap of reads with genes. Availability and implementation: HTSeq is released as an open-source software under the GNU General Public Licence and available from http://www-huber.embl.de/HTSeq or from the Python Package Index at https://pypi.python.org/pypi/HTSeq. Contact: sanders@fs.tum.de
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DOI:
10.1093/bioinformatics/btq033
发表时间:
2010-03-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Quinlan AR;Hall IM
通讯作者:
Hall IM
DOI:
10.1093/bioinformatics/btp163
发表时间:
2009-06-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Cock PJ;Antao T;Chang JT;Chapman BA;Cox CJ;Dalke A;Friedberg I;Hamelryck T;Kauff F;Wilczynski B;de Hoon MJ
通讯作者:
de Hoon MJ
影响因子:
12.3
作者:
Gentleman RC;Carey VJ;Bates DM;Bolstad B;Dettling M;Dudoit S;Ellis B;Gautier L;Ge Y;Gentry J;Hornik K;Hothorn T;Huber W;Iacus S;Irizarry R;Leisch F;Li C;Maechler M;Rossini AJ;Sawitzki G;Smith C;Smyth G;Tierney L;Yang JY;Zhang J
通讯作者:
Zhang J
影响因子:
2.1
作者:
van der Walt, Stefan;Colbert, S. Chris;Varoquaux, Gael
通讯作者:
Varoquaux, Gael
DOI:
10.1093/bioinformatics/btr539
发表时间:
2011-12-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Dale RK;Pedersen BS;Quinlan AR
通讯作者:
Quinlan AR