Circumferential strain in the wall of the common carotid artery: comparing displacement-encoded and cine MRI in volunteers.

Circumferential strain in the wall of the common carotid artery: comparing displacement-encoded and cine MRI in volunteers.
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DOI:
10.1002/mrm.21621
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发表时间:
2008-07
影响因子:
3.3
通讯作者:
Wen, Han
Wen, Han
中科院分区:
医学3区
文献类型:
--
作者:
Lin, Alexander P.;Bennett, Eric;Wisk, Lauren E.;Gharib, Morteza;Fraser, Scott E.;Wen, Han

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管道动脉的壁经受来自动脉压的周期性波动的周期性拉伸。动脉粥样硬化病变已被证明局限于动脉壁过度拉伸的区域。我们采用了位移编码与刺激回波(DENSE)序列的图像颈总动脉壁的运动和地图的二维(2D)的圆周应变。该序列采用全平衡稳态自由旋进(SSFP)读数,面内分辨率为0.60 mm。将志愿者在1.5T(N = 4)和3.0T(N = 17)下的初步结果与电影图像中的管腔周长测量值进行比较。在两种场强下的两次独立测量结果之间的一致性(P ≤ 0.001)支持使用DENSE作为颈动脉壁脉动应变标测的方法。
The walls of conduit arteries undergo cyclic stretching from the periodic fluctuation of arterial pressure. Atherosclerotic lesions have been shown to localize to regions of excessive stretching of the arterial wall. We employed a displacement encoding with stimulated echoes (DENSE) sequence to image the motion of the common carotid artery wall and map the two-dimensional (2D) circumferential strain. The sequence utilizes a fully-balanced steady-state free-precession (SSFP) readout with 0.60 mm in-plane resolution. Preliminary results in volunteers at 1.5T (N = 4) and 3.0T (N = 17) are compared to measurements of the lumen circumference from cine images. The agreement between the two independent measurements at both field strengths (P ≤ 0.001) supports the use of DENSE as a means to map the pulsatile strain in the carotid artery wall.
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