Patient-Doctor Contact Interval and Clinical Outcomes in Continuous Ambulatory Peritoneal Dialysis Patients
Patient-Doctor Contact Interval and Clinical Outcomes in Continuous Ambulatory Peritoneal Dialysis Patients
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连续门诊腹膜透析患者的医患接触间隔和临床结果
DOI：
10.1159/000464258
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发表时间：
2017-03
影响因子：
4.2
通讯作者：
Yang Xiao
中科院分区：
文献类型：
--
作者：
Yi Chunyan;Guo Qunying;Lin Jianxiong;Li Jianying;Yu Xueqing;Yang Xiao
背景：腹膜透析（PD）患者的最佳医患接触（PDC）时间间隔尚不清楚。目的是研究连续动态PD （CAPD）患者PDC间隔与临床结果之间的关系。方法：回顾性队列研究纳入2006年1月至2012年12月在广州市居住的CAPD患者。根据受试者工作特征曲线分析，将患者分为PDC频率高组（PDC间隔≤2个月）和PDC频率低组（PDC间隔>2个月）。比较随访期间的生化数据、临床事件和临床结果。结果：433例CAPD患者平均年龄51.3±15.7岁，男性占54.3%，糖尿病占29.1%。PD的中位病程为45.8（26.3-69.1）个月。与低PDC频率组（n = 200）相比，高PDC频率组（n = 233）的患者生存率更高（1年、3年和5年生存率分别为99.6%、87.7和76.5% vs. 92.7、76.5和58.7%,p < 0.001），腹膜炎发生率更低（0.17 vs. 0.23次/患者-年，p < 0.001），住院率（0.49 vs. 0.67次/患者-年，p < 0.001）。调整混杂因素后，不超过2个月的PDC间隔与更好的患者生存率独立相关（风险比0.60,95% CI 0.42-0.86, p = 0.006）。结论：2个月或更短的PDC间隔与CAPD患者更好的临床结果相关。这表明应鼓励缩短PDC间隔以获得更好的临床效果。
Background: The optimal patient-doctor contact (PDC) interval remains unknown in peritoneal dialysis (PD) patients. The aim was to investigate the association between PDC interval and clinical outcomes in continuous ambulatory PD (CAPD) patients. Methods: In this retrospective cohort study, CAPD patients who resided in Guangzhou city between January 2006 and December 2012 were included. According to receiver operating characteristic curve analysis, all patients were classified as high (PDC interval ≤2 months) and low (PDC interval >2 months) PDC frequency groups. Biochemical data, clinical events, and clinical outcomes during the follow-up period were compared. Results: Of 433 CAPD patients, the mean age was 51.3 ± 15.7 years, 54.3% of patients were male, and 29.1% with diabetes. The median vintage of PD was 45.8 (26.3-69.1) months. Patients with high PDC frequency (n = 233) had better patient-survival rates (99.6, 87.7, and 76.5% vs. 92.7, 76.5, and 58.7% at 1, 3, and 5 years; p < 0.001), lower peritonitis rate (0.17 vs. 0.23 episodes per patient-year; p < 0.001), and hospitalization rate (0.49 vs. 0.67 episodes per patient-year; p < 0.001) than those in the low PDC frequency group (n = 200). After adjustment for confounders, PDC interval of no more than 2 months was independently associated with better patient survival (hazard ratio 0.60, 95% CI 0.42-0.86, p = 0.006). Conclusion: A PDC interval of 2 months or less was associated with better clinical outcomes in CAPD patients. This indicates that a shorter PDC interval should be encouraged for them to achieve better clinical outcomes.
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影响因子：
2.6
作者：
Plantinga, LC;Jaar, BG;Powe, NR
通讯作者：
Powe, NR
DOI：
10.1097/01.asn.0000106101.48237.9d
发表时间：
2004-01-01
影响因子：
13.6
作者：
Plantinga, LC;Fink, NE;Powe, NR
通讯作者：
Powe, NR
影响因子：
--
作者：
Yumi Kimura;Tsutomu Inoue;Hiromichi Suzuki
通讯作者：
Yumi Kimura;Tsutomu Inoue;Hiromichi Suzuki
影响因子：
13.6
作者：
Kawaguchi, Takehiko;Karaboyas, Angelo;Saran, Rajiv
通讯作者：
Saran, Rajiv
DOI：
--
发表时间：
1998-10
期刊：
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
影响因子：
--
作者：
N. Roos;K. Carriere;D. Friesen
通讯作者：
N. Roos;K. Carriere;D. Friesen