Localized high-resolution DTI of the human midbrain using single-shot EPI, parallel imaging, and outer-volume suppression at 7T.
Localized high-resolution DTI of the human midbrain using single-shot EPI, parallel imaging, and outer-volume suppression at 7T.
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DOI：
10.1016/j.mri.2013.01.013
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发表时间：
2013-07
影响因子：
2.5
通讯作者：
Gore, John C.
中科院分区：
文献类型：
--
作者：
Wargo, Christopher J.;Gore, John C.
Localized high-resolution diffusion tensor images (DTI) from the midbrain were obtained using reduced field-of-view (rFOV) methods combined with SENSE parallel imaging and single-shot echo planar (EPI) acquisitions at 7 T. This combination aimed to diminish sensitivities of DTI to motion, susceptibility variations, and EPI artifacts at ultra-high field. Outer-volume suppression (OVS) was applied in DTI acquisitions at 2- and 1-mm2 resolutions, b=1000 s/mm2, and six diffusion directions, resulting in scans of 7- and 14-min durations. Mean apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values were measured in various fiber tract locations at the two resolutions and compared. Geometric distortion and signal-to-noise ratio (SNR) were additionally measured and compared for reduced-FOV and full-FOV DTI scans. Up to an eight-fold data reduction was achieved using DTI-OVS with SENSE at 1 mm2, and geometric distortion was halved. The localization of fiber tracts was improved, enabling targeted FA and ADC measurements. Significant differences in diffusion properties were observed between resolutions for a number of regions suggesting that FA values are impacted by partial volume effects even at a 2-mm2 resolution. The combined SENSE DTI-OVS approach allows large reductions in DTI data acquisition and provides improved quality for high-resolution diffusion studies of the human brain.
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影响因子：
2.3
作者：
Alexander, AL;Lee, JE;Field, AS
通讯作者：
Field, AS
影响因子：
3.5
作者：
Chen, H. J.;Panigrahy, A.;Blueml, S.
通讯作者：
Blueml, S.
影响因子：
4.4
作者：
Finsterbusch, Juergen
通讯作者：
Finsterbusch, Juergen
影响因子：
3.3
作者：
Griswold, MA;Jakob, PM;Haase, A
通讯作者：
Haase, A
DOI：
10.1002/jmri.1880080505
发表时间：
1998-09-01
期刊：
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING
影响因子：
--
作者：
Le Roux, P;Gilles, RJ;Carlier, PG
通讯作者：
Carlier, PG