Development of symptoms of tobacco dependence in youths: 30 month follow up data from the DANDY study
Development of symptoms of tobacco dependence in youths: 30 month follow up data from the DANDY study
复制标题
青少年烟草依赖症状的发展：DANDY 研究的 30 个月随访数据
作者：
J. Difranza;J. Savageau;N. Rigotti;K. Fletcher;J. Ockene;A. McNeill;Mardia A. Coleman;C. Wood
目的：确定是否存在形成依赖症状所需的最低烟草使用持续时间、频率或数量。设计和设置：一项回顾性/前瞻性纵向研究的自然历史的烟草依赖，采用个人访谈进行了三次，每年在两个城市的学校系统超过30个月。获得了烟草使用的详细历史，包括日期、持续时间、频率、数量、使用模式、烟草类型和依赖症状。参与者：一组679名七年级学生（年龄12-13岁）。主要观察指标：报告11种依赖症状。结果如下：在332名曾吸烟的受试者中，40%的人报告了症状，女孩每月吸烟的中位潜伏期为21天，男孩为183天。出现症状时的中位使用频率为两支香烟，每周一天。一个或多个症状的报告预测持续吸烟到随访结束（比值比（OR）44，95%置信区间（CI）17至114，p < 0.001）。结论：烟草依赖的症状通常在间歇性吸烟开始后迅速发展，尽管在这方面个体差异很大。女孩往往会更快地出现症状。似乎没有最低尼古丁剂量或使用持续时间作为出现症状的先决条件。单一症状的发展强烈预测了持续使用，支持了烟草使用自主权的丧失始于依赖的第一个症状的理论。
Objective: To determine if there is a minimum duration, frequency or quantity of tobacco use required to develop symptoms of dependence. Design and setting: A retrospective/prospective longitudinal study of the natural history of tobacco dependence employing individual interviews conducted three times annually in two urban school systems over 30 months. Detailed histories of tobacco use were obtained including dates, duration, frequency, quantity, patterns of use, types of tobacco, and symptoms of dependence. Participants: A cohort of 679 seventh grade students (age 12–13 years). Main outcome measures: The report of any of 11 symptoms of dependence. Results: Among 332 subjects who had used tobacco, 40% reported symptoms, with a median latency from the onset of monthly smoking of 21 days for girls and 183 days for boys. The median frequency of use at the onset of symptoms was two cigarettes, one day per week. The report of one or more symptoms predicted continued smoking through the end of follow up (odds ratio (OR) 44, 95% confidence interval (CI) 17 to 114, p < 0.001). Conclusions: Symptoms of tobacco dependence commonly develop rapidly after the onset of intermittent smoking, although individuals differ widely in this regard. Girls tend to develop symptoms faster. There does not appear to be a minimum nicotine dose or duration of use as a prerequisite for symptoms to appear. The development of a single symptom strongly predicted continued use, supporting the theory that the loss of autonomy over tobacco use begins with the first symptom of dependence.
登录
查看更多内容
完善依赖模型：人和情况之间的差异。
DOI：
10.1111/j.1360-0443.1991.tb01817.x
发表时间：
1991
期刊：
British journal of addiction
影响因子：
--
作者：
Shiffman,S
通讯作者：
Shiffman,S
尼古丁依赖和 Fagerström 耐受性调查问卷：简要回顾。
DOI：
--
发表时间：
1989
期刊：
Journal of substance abuse
影响因子：
--
作者：
Pomerleau,CS;Majchrzak,MJ;Pomerleau,OF
通讯作者：
Pomerleau,OF
从幼年期到成年期，去神经大鼠海马的突触替换率急剧下降。
DOI：
10.1126/science.6867730
发表时间：
1983
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
McWilliams,JR;Lynch,G
通讯作者：
Lynch,G
吸烟的自然史：根据青少年吸烟模式预测年轻成人吸烟结果。
DOI：
10.1037//0278-6133.9.6.701
发表时间：
1990
期刊：
Health psychology : official journal of the Division of Health Psychology, American Psychological Association
影响因子：
--
作者：
Chassin,L;Presson,CC;Sherman,SJ;Edwards,DA
通讯作者：
Edwards,DA
影响因子：
4.2
作者：
Colby,SM;Tiffany,ST;Shiffman,S;Niaura,RS
通讯作者：
Niaura,RS