Dendritic inclusions in the cerebellar granular layer after long term alcohol consumption in adult rats.
Dendritic inclusions in the cerebellar granular layer after long term alcohol consumption in adult rats.
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成年大鼠长期饮酒后小脑颗粒层中的树突状内含物。
DOI：
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
B. Volk
中科院分区：
文献类型：
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作者：
M. Tavares;M. M. Barbosa;E. Gray;B. Volk
经过 6 个月的酒精处理后，在小脑高尔基体细胞的树突中观察到直径达 1.5 微米的轮生多平面包涵体，并且数量随着时间的推移而增加。内含物由平行或扭曲排列的并列细胞膜形成。成对的膜融合成致密、质地细腻的材料。与树突状光滑内质网的密切关系是显而易见的。尽管与许多其他类型的神经元细胞质内含物一样，它们的起源和功能仍有待确定，但慢性酒精摄入与这些内含物的发育之间存在相关性。
Whorled multiplanal inclusions up to 1.5 micron in diameter were observed in dendrites of the cerebellar Golgi cells after 6 months of alcohol treatment, increasing in number with time. Inclusions are formed by apposed cytomembranes stacked parallel or in a twisted arrangement. The paired membranes merged into a dense, finely textured material. A close relationship with dendritic smooth endoplasmic reticulum is apparent. A correlation between chronic alcohol intake and the development of these inclusions is shown although, in common with many other types of neuronal cytoplasmic inclusions, their genesis and function remains to be determined.
动物长期服用乙醇后的神经解剖学和功能缺陷。
DOI：
10.1111/j.1530-0277.1981.tb04901.x
发表时间：
1981
期刊：
Alcoholism, clinical and experimental research
影响因子：
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作者：
Walker,DW;Hunter,BE;Abraham,WC
通讯作者：
Abraham,WC