A virus-derived small RNA targets the rice transcription factor ROC1 to induce disease-like symptom
A virus-derived small RNA targets the rice transcription factor ROC1 to induce disease-like symptom
复制标题
病毒衍生的小RNA靶向水稻转录因子ROC1以诱导疾病样症状
DOI:
10.1186/s42483-022-00112-6
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发表时间:
2022-03
影响因子:
3.4
通讯作者:
Tong Zhang
中科院分区:
文献类型:
--
作者:
Xiuqin Huang;Feifei Li;Xishan Zhang;Jiahao Chen;Junkai Wang;Jing Wei;Xin Yang;Guohui Zhou;Tong Zhang
Virus-derived small interfering RNAs (vsiRNAs) in plants can target host transcripts to induce symptom development. Southern rice black-streaked dwarf virus (SRBSDV) is the most damaging rice-infecting virus, which causes severe stunting and poorly developed roots in rice plants, thereby posing a serious threat to rice production. In this study, we show that a vsiRNA (vsiR-S9-18), generated from SRBSDV genome segment 9, targets the transcription factor ROC1 in rice. SRBSDV infection triggered the production of vsiR-S9-18 and resulted in the downregulation ofROC1in rice plants. Transient expression of vsiR-S9-18 in rice protoplasts and tobacco leaves further demonstrated the specific association of vsiR-S9-18 withROC1. Moreover, theROC1-knockout rice plants displayed shortened roots, similar to the phenotype of root growth inhibition caused by SRBSDV infection. We propose that vsiR-S9-18 inhibits root elongation viaROC1, which has been proven to regulate root growth. This finding extends our understanding of the role of vsiRNA in viral disease development and is helpful for the development of new antiviral approaches.
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影响因子:
5.3
作者:
通讯作者:
--
影响因子:
14.9
作者:
Dai X;Zhao PX
通讯作者:
Zhao PX
影响因子:
27.5
作者:
Yaling Zhao;Xue Cao;Weihua Zhong;Shunkang Zhou;Zhanbiao Li;Hong An;Xiahua Liu;Ruifeng Wu;Surakshya Bohora;Yan Wu;Zhenyi Liang;Jiahao Chen;Xin Yang;Guohui Zhou;Tong Zhang
通讯作者:
Tong Zhang
DOI:
10.3390/v10110594
发表时间:
2018-10-30
期刊:
Viruses
影响因子:
--
作者:
Li Z;Zhang T;Huang X;Zhou G
通讯作者:
Zhou G
影响因子:
10.7
作者:
Zalewski CS;Floyd SK;Furumizu C;Sakakibara K;Stevenson DW;Bowman JL
通讯作者:
Bowman JL