Optimal k-space sampling for dynamic contrast-enhanced MRI with an application to MR renography.
Optimal k-space sampling for dynamic contrast-enhanced MRI with an application to MR renography.
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DOI：
10.1002/mrm.21901
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发表时间：
2009-05
影响因子：
3.3
通讯作者：
Lee, Vivian S.
中科院分区：
文献类型：
--
作者：
Song, Ting;Laine, Andrew F.;Chen, Qun;Rusinek, Henry;Bokacheva, Louisa;Lim, Ruth P.;Laub, Gerhard;Kroeker, Randall;Lee, Vivian S.
对于使用K空间底采样的时间分辨的采集，开发了一种模拟方法，用于选择基于信号强度与时间和生理参数的误差最小化的成像参数。使用用于对比增强肾脏术的随机轨迹（Twist）算法的时间分辨血管造影进行了优化。由主动脉和两个肾脏组成的现实4D幻影，一种健康和一种患病的肾脏是由理想的组织时间增强模式创建的，该模式使用具有固定参数的三室模型产生，包括肾小球过滤率（GFR）和肾脏等离子体流量（RPF）（RPF） ）。将采样的中央和周围k空间部分的不同组合进行了扭曲采集。通过模拟信号强度（SI）和计算出的GFR和RPF及其理想值之间的差异来评估采集性能。在相位编码平面中对中心的20％和k-space的1/5进行采样，其余4/5的数据共享将Si（<5％），RPF和GFR的误差最小化（RPF）和GFR（健康肾脏和患病的肾脏都<10％）。使用最佳扭曲参数和2.4秒的时间分辨率获得了高质量的动态人类图像。所提出的方法可以推广到其他动态对比度增强的MRI应用，例如MR血管造影或癌症成像。
For time-resolved acquisitions with k-space undersampling, a simulation method was developed for selecting imaging parameters based on minimization of errors in signal intensity versus time and physiologic parameters derived from tracer kinetic analysis. Optimization was performed for time-resolved angiography with stochastic trajectories (TWIST) algorithm applied to contrast-enhanced MR renography. A realistic 4D phantom comprised of aorta and two kidneys, one healthy and one diseased, was created with ideal tissue time-enhancement pattern generated using a three-compartment model with fixed parameters, including glomerular filtration rate (GFR) and renal plasma flow (RPF). TWIST acquisitions with different combinations of sampled central and peripheral k-space portions were applied to this phantom. Acquisition performance was assessed by the difference between simulated signal intensity (SI) and calculated GFR and RPF and their ideal values. Sampling of the 20% of the center and 1/5 of the periphery of k-space in phase-encoding plane and data-sharing of the remaining 4/5 minimized the errors in SI (<5%), RPF, and GFR (both <10% for both healthy and diseased kidneys). High-quality dynamic human images were acquired with optimal TWIST parameters and 2.4 sec temporal resolution. The proposed method can be generalized to other dynamic contrast-enhanced MRI applications, e.g., MR angiography or cancer imaging.
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影响因子：
3.3
作者：
Tsao, J;Boesiger, P;Pruessmann, KP
通讯作者：
Pruessmann, KP
影响因子：
19.7
作者：
Sadowski, Elizabeth A.;Bennett, Lindsey K.;Djamali, Arjang
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影响因子：
3.3
作者：
PARRISH, T;HU, XP
通讯作者：
HU, XP
影响因子：
3.3
作者：
Bokacheva, Louisa;Rusinek, Henry;Lee, Vivian S.
通讯作者：
Lee, Vivian S.
影响因子：
19.7
作者：
Lee, VS;Rusinek, H;Kramer, EL
通讯作者：
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