Naturalistic conceptions of genetic optimism and precision psychiatry among those at clinical high-risk for psychosis.

Naturalistic conceptions of genetic optimism and precision psychiatry among those at clinical high-risk for psychosis.
复制标题

精神病临床高危人群的遗传乐观主义和精确精神病学的自然主义观念。

DOI:
10.1111/eip.12983
复制
发表时间:
2021-06
影响因子:
2
通讯作者:
Yang, Lawrence H.
Yang, Lawrence H.
中科院分区:
医学3区
文献类型:
--
作者:
Blasco, Drew;Stortz, Saige William;Grivel, Margaux Marie-Rose;Dishy, Gabriella A.;Samuel, Shana S.;Pilla, David;Crump, Francesca M.;Lieff, Sarah A.;Williams, Jourdan;Phoummavong, Phetsamone;Guo, Xufei;Brucato, Gary;Girgis, Ragy R.;Yang, Lawrence H.

文献摘要

参考文献

相似文献

在基因组学进步的推动下,最近对“精准医学”概念的强调,以及公众对遗传进步的乐观态度,重要的是要了解那些被认为是精神病临床高风险的人如何看待基因检测的可能益处,以告知未来的利益相关者教育工作。半结构化的采访完成了20名参与者谁符合ESTA标准。遗传乐观的编码已经完成。与会者赞同遗传学之间的联系的许多概念化,精神病的发展,以及基因检测的好处。具体而言,围绕基因检测如何可能导致更多的遗传知识和量身定制的治疗出现了主题。我们的研究结果表明,研究参与者普遍赞同几个精确的精神病学概念,包括基因检测如何可能导致量身定制的治疗进展。这方面的知识可能有助于制定最佳的沟通做法,即将在诊断和治疗中的CHR基因的进步。
Fueled by genomics advances, recent emphasis on the concept of “precision medicine,” and public optimism towards genetic advances, it is important to understand how those who are considered to be at clinical high-risk for psychosis (CHR) perceive possible benefits of genetic testing to inform future stakeholder education efforts. Semi-structured interviews were completed with 20 participants who met CHR criteria. Coding for genetic optimism was completed. Participants endorsed many conceptualizations of the link between genetics, the development of psychosis, and the benefits of genetic testing. Specifically, themes emerged surrounding how genetic testing may lead to greater genetic knowledge and tailored treatment. Our results demonstrate that CHR participants generally endorse several precision psychiatry concepts, including how genetic testing may lead to tailored treatment advances. This knowledge may aid development of best communication practices regarding forthcoming genetic advances in diagnosis and treatment among CHR.
DOI: 10.1023/a:1010690427114
发表时间: 2001-01-01
影响因子: 1.7
作者:
Conrad, P
通讯作者: Conrad, P
DOI: 10.1093/oxfordjournals.schbul.a007040
发表时间: 2003-01-01
影响因子: 6.6
作者:
Miller, TJ;McGlashan, TH;Woods, SW
通讯作者: Woods, SW
DOI: 10.1017/s003329171300072x
发表时间: 2014-01-01
影响因子: 6.9
作者:
Schomerus, G.;Matschinger, H.;Angermeyer, M. C.
通讯作者: Angermeyer, M. C.
DOI: 10.1002/ajmg.b.30249
发表时间: 2006-01-05
影响因子: 2.8
作者:
DeLisi, LE;Bertisch, H
通讯作者: Bertisch, H
DOI: 10.1016/j.socscimed.2008.07.007
发表时间: 2008-11-01
影响因子: 5.4
作者:
Schnittker, Jason
通讯作者: Schnittker, Jason