Randomized Controlled Trial of Advance Notification Phone Calls vs Text Messages Prior to Mailed Fecal Test Outreach.

Randomized Controlled Trial of Advance Notification Phone Calls vs Text Messages Prior to Mailed Fecal Test Outreach.
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DOI:
10.1016/j.cgh.2020.07.053
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发表时间:
2021-11
期刊:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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其他
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邮寄粪便免疫化学测试(FIT)到个人谁是由于筛选(邮寄FIT推广)增加结直肠癌(CRC)筛查。很少有人知道如何基于电话的预先通知(引物)影响邮寄FIT外展计划的有效性。我们对一家大型城市健康中心的患者进行了一项前瞻性研究,这些患者年龄在50-75岁之间,应进行筛查,既往没有FIT记录。参与者被随机分配到2018年6月至12月期间接受现场电话入门(n = 1203)或短信入门(n = 1622)的组。然后,参与者被邮寄FIT套件,随后是2个自动电话,以及护理团队提供的实时提醒电话。主要结果是在分配到现场电话或短信组的3个月内完成FIT。参与者的FIT完成率为16.8%,平均年龄为58岁,80%为拉丁美洲人。在调整后的意向治疗分析中(n = 2825),分配接受实时电话呼叫的患者的FIT完成率高于接受短信引导的患者(百分点差异,3.3%; 95% CI,0.4%-6.2%)。在通过短信(1320/1622,81%)、实时电话(438/1203,36%)或语音消息(386/1203,32%)联系的2144名参与者的符合方案分析中,组间差异增加至7.3%(95% CI,3.6%-11.0%)。在对通过短信或现场电话联系的1758名参与者进行的符合方案分析中,该比率增加至14.9%(95% CI; 9.6%-20.1%)。在一项随机试验中,提前通知实时电话在提示以前没有完成FIT的健康中心患者完成邮寄FIT方面优于短信。Clinicaltrials.gov编号:NCT 03167125
Mailing fecal immunochemical test (FITs) to individuals who are due for screening (mailed FIT outreach) increases colorectal cancer (CRC) screening. Little is known about how phone-based advance notifications (primers) affect the effectiveness of mailed FIT outreach programs. We performed a prospective study of patients at a large urban health center, 50–75 years old and due for screening, with no record of a prior FIT. Participants were randomly assigned to groups that received a live phone call primer (n = 1203) or a text message primer (n = 1622), from June through December 2018. The participants were then mailed a FIT kit, followed by 2 automated calls, and live reminder calls delivered by the care team. The main outcome was completion of FIT within 3 months of assignment to the live phone call or text message group. Participants had a FIT completion rate of 16.8%, a mean age of 58 years, and 80% were Latino. In adjusted intention to treat analyses (n = 2825), FIT completion rates were higher in the patients assigned to receive a live phone call vs text message primer (percentage point difference, 3.3%; 95% CI, 0.4%–6.2%). Between-group differences increased to 7.3% points (95% CI, 3.6%–11.0%) in the per-protocol analysis of 2144 participants reached by the text message (1320/1622, 81%), live call (438/1203, 36%), or voice message (386/1203, 32%). This rate increased to 14.9% points (95% CI; 9.6%–20.1%) in the per-protocol analysis of 1758 participants reached by the text message or reached by the live call. In a randomized trial, advance notification live phone calls outperformed text messages in prompting health center patients who had not previously completed a FIT to complete a mailed FIT. Clinicaltrials.gov no: NCT03167125
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