Graphene oxide-based fluorescent detection of DNA and enzymes using Hoechst 33258 and its use for dual-output fluorescent logic gates
Graphene oxide-based fluorescent detection of DNA and enzymes using Hoechst 33258 and its use for dual-output fluorescent logic gates
复制标题
使用 Hoechst 33258 基于氧化石墨烯的 DNA 和酶荧光检测及其在双输出荧光逻辑门中的应用
DOI:
10.1039/c3ay40581h
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发表时间:
2013-07
影响因子:
3.1
通讯作者:
Zhou, Xiang
中科院分区:
文献类型:
--
作者:
Yan, Shengyong;Huang, Rong;Weng, Xiaocheng;Zhou, Xiang
Based on graphene oxide and Hoechst 33258, bioassays towards target DNA and several enzymes including Exo III and Dam MTase were established. This strategy eliminates the need for modification of oligonucleotides, and can give similarly satisfactory results compared to traditional methods using labelled DNA. Moreover, “AND” and “INHIBIT” dual-output DNA logic gates were developed.
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