Feasibility of Measuring Preferences for Chemotherapy Among Early-Stage Breast Cancer Survivors Using a Direct Rank Ordering Multicriteria Decision Analysis Versus a Time Trade-Off.
Feasibility of Measuring Preferences for Chemotherapy Among Early-Stage Breast Cancer Survivors Using a Direct Rank Ordering Multicriteria Decision Analysis Versus a Time Trade-Off.
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DOI：
10.1007/s40271-020-00423-w
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发表时间：
2020-10
期刊：
影响因子：
--
通讯作者：
Ramsey SD
中科院分区：
文献类型：
--
作者：
Panattoni L;Phelps CE;Lieu TA;Alexeeff S;O'Neill S;Mandelblatt JS;Ramsey SD
Chemotherapy is increasingly a preference-based choice among women diagnosed with early stage breast cancer. Multi-criteria decision analysis (MCDA) is a promising but underutilized method to facilitate shared decision-making. We explored the feasibility of conducting a MCDA using direct rank ordering versus a time tradeoff (TTO) to assess chemotherapy choice in a large population-based sample. We surveyed 904 early stage breast cancer survivors who were within 5 years of diagnosis and reported to the Western Washington State Cancer System and Kaiser Permanente Northern California registries. Direct rank ordering of 11 criteria and TTO surveys were conducted from September 2015-July 2016; clinical data were obtained from registries or medical records. Multivariable regressions estimated post-hoc associations between the MCDA, TTO, and self-reported chemotherapy receipt, considering covariates. Survivors ranged in age from 25–74 and 73.9% had stage 1 tumors. The response rate for the rank ordering was 81.0%; TTO score was 94.2%. A one-standard deviation increase in the difference between the chemotherapy and no chemotherapy MCDA scores was associated with a 75.1% (95% CI 43.9%−109.7%, p<0.001) increase in the adjusted odds of having received chemotherapy; no association was found between the TTO score and chemotherapy receipt. A rank-order based MCDA was feasible and associated with chemotherapy choice. Future research should consider developing and testing this MCDA for use in clinical encounters. Additional research is required to develop a TTO-based model and test its properties against a pragmatic MCDA to inform future shared decision-making tools. Multi-criteria decision analysis but not time trade off based preferences were associated with chemotherapy receipt but had a lower response rate (81% versus 94%).
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DOI：
10.2165/11539470-000000000-00000
发表时间：
2010
期刊：
The patient
影响因子：
--
作者：
Dolan JG
通讯作者：
Dolan JG
基因表达谱测试对化学疗法决策和预后期望的信心的影响。
影响因子：
3.8
作者：
Panattoni L;Lieu TA;Jayasekera J;O'Neill S;Mandelblatt JS;Etzioni R;Phelps CE;Ramsey SD
通讯作者：
Ramsey SD
DOI：
10.2165/11587140-000000000-00000
发表时间：
2012-03-01
影响因子：
3.6
作者：
IJzerman, Maarten J.;van Til, Janine A.;Bridges, John F. P.
通讯作者：
Bridges, John F. P.
影响因子：
2.7
作者：
Balinski, Michel;Laraki, Rida
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Laraki, Rida
影响因子：
4.5
作者：
Phelps, Charles E.;Madhavan, Guruprasad
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Madhavan, Guruprasad