DichroMatch: a website for similarity searching of circular dichroism spectra.
DichroMatch: a website for similarity searching of circular dichroism spectra.
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DOI:
10.1093/nar/gks449
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发表时间:
2012-07
影响因子:
14.9
通讯作者:
Janes RW
中科院分区:
文献类型:
--
作者:
Klose DP;Wallace BA;Janes RW
Circular dichroism (CD) spectroscopy is a widely used method for examining the structure, folding and conformational changes of proteins. A new online CD analysis server (DichroMatch) has been developed for identifying proteins with similar spectral characteristics by detecting possible structurally and functionally related proteins and homologues. DichroMatch includes six different methods for determining the spectral nearest neighbours to a query protein spectrum and provides metrics of how similar these spectra are and, if corresponding crystal structures are available for the closest matched proteins, information on their secondary structures and fold classifications. By default, DichroMatch uses all the entries in the Protein Circular Dichroism Data Bank (PCDDB) for its comparison set, providing the broadest range of publicly available protein spectra to match with the unknown protein. Alternatively, users can download or create their own specialized data sets, thereby enabling comparisons between the structures of related proteins such as wild-type versus mutants or homologues or a series of spectra of the same protein under different conditions. The DichroMatch server is freely available at http://dichromatch.cryst.bbk.ac.uk.
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影响因子:
2.9
作者:
HENNESSEY, JP;JOHNSON, WC
通讯作者:
JOHNSON, WC
影响因子:
5.8
作者:
Abdul-Gader, Ali;Miles, Andrew John;Wallace, B. A.
通讯作者:
Wallace, B. A.
影响因子:
14.9
作者:
Whitmore L;Woollett B;Miles AJ;Klose DP;Janes RW;Wallace BA
通讯作者:
Wallace BA
影响因子:
--
作者:
Miles, AJ;Wien, F;Wallace, BA
通讯作者:
Wallace, BA
影响因子:
3
作者:
Lees, Jonathan G.;Miles, Andrew J.;Wallace, B. A.
通讯作者:
Wallace, B. A.