Cortical cross-frequency coupling predicts perceptual outcomes.
Cortical cross-frequency coupling predicts perceptual outcomes.
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DOI：
10.1016/j.neuroimage.2012.11.021
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发表时间：
2013-04-01
期刊：
影响因子：
5.7
通讯作者：
Foxe JJ
中科院分区：
文献类型：
--
作者：
Fiebelkorn IC;Snyder AC;Mercier MR;Butler JS;Molholm S;Foxe JJ
功能网络是由神经元集合通过多个内在振荡频率的同步而结合而成的。已经描述了脑振荡器之间的各种耦合交互（例如，相位-振幅耦合），但几乎没有证据表明这些相互作用实际上影响感知灵敏度。在这里，在持续注意任务期间进行脑电图（EEG）记录，以证明交叉频率耦合对感知结果具有显著影响（即，参与者是否检测到接近阈值的视觉目标）。数据显示，在较高频率的相位检测关系取决于较低频率的相位，使得较高频率在其相位对视觉目标检测的预测性强或弱的时期之间交替。此外，与视觉目标检测相关的特定较高频率和头皮形貌也作为较低频率相位的函数而交替。较低频率（即，δ和θ）和更高的频率（例如，低β和高β）因此导致视觉目标检测的剧烈波动。
Functional networks are comprised of neuronal ensembles bound through synchronization across multiple intrinsic oscillatory frequencies. Various coupled interactions between brain oscillators have been described (e.g., phase-amplitude coupling), but with little evidence that these interactions actually influence perceptual sensitivity. Here, electroencephalographic (EEG) recordings were made during a sustained-attention task to demonstrate that cross-frequency coupling has significant consequences for perceptual outcomes (i.e., whether participants detect a near-threshold visual target). The data reveal that phase-detection relationships at higher frequencies are dependent on the phase of lower frequencies, such that higher frequencies alternate between periods when their phase is either strongly or weakly predictive of visual-target detection. Moreover, the specific higher frequencies and scalp topographies linked to visual-target detection also alternate as a function of lower-frequency phase. Cross-frequency coupling between lower (i.e., delta and theta) and higher frequencies (e.g., low- and high-beta) thus results in dramatic fluctuations of visual-target detection.
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DOI：
10.1523/jneurosci.1338-11.2011
发表时间：
2011-07-06
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Fiebelkorn IC;Foxe JJ;Butler JS;Mercier MR;Snyder AC;Molholm S
通讯作者：
Molholm S
DOI：
10.1523/jneurosci.2164-11.2011
发表时间：
2011-12-14
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Gomez-Ramirez M;Kelly SP;Molholm S;Sehatpour P;Schwartz TH;Foxe JJ
通讯作者：
Foxe JJ
影响因子：
5.3
作者：
Busch, Niko A.;Dubois, Julien;VanRullen, Rufin
通讯作者：
VanRullen, Rufin
影响因子：
5.7
作者：
Genovese, CR;Lazar, NA;Nichols, T
通讯作者：
Nichols, T
DOI：
10.1523/jneurosci.4122-11.2012
发表时间：
2012-01-11
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Belluscio MA;Mizuseki K;Schmidt R;Kempter R;Buzsáki G
通讯作者：
Buzsáki G