cblaster: a remote search tool for rapid identification and visualization of homologous gene clusters.
cblaster: a remote search tool for rapid identification and visualization of homologous gene clusters.
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DOI:
10.1093/bioadv/vbab016
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发表时间:
2021
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--
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Genes involved in coordinated biological pathways, including metabolism, drug resistance and virulence, are often collocalized as gene clusters. Identifying homologous gene clusters aids in the study of their function and evolution, however, existing tools are limited to searching local sequence databases. Tools for remotely searching public databases are necessary to keep pace with the rapid growth of online genomic data. Here, we present cblaster, a Python-based tool to rapidly detect collocated genes in local and remote databases. cblaster is easy to use, offering both a command line and a user-friendly graphical user interface. It generates outputs that enable intuitive visualizations of large datasets and can be readily incorporated into larger bioinformatic pipelines. cblaster is a significant update to the comparative genomics toolbox. cblaster source code and documentation is freely available from GitHub under the MIT license (github.com/gamcil/cblaster). Supplementary data are available at Bioinformatics Advances online.
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影响因子:
10.7
作者:
Medema MH;Takano E;Breitling R
通讯作者:
Breitling R
DOI:
10.1093/bioinformatics/btp163
发表时间:
2009-06-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Cock PJ;Antao T;Chang JT;Chapman BA;Cox CJ;Dalke A;Friedberg I;Hamelryck T;Kauff F;Wilczynski B;de Hoon MJ
通讯作者:
de Hoon MJ
影响因子:
9.4
作者:
Liu, Zhenhua;Duran, Hernando G. Suarez;Osbourn, Anne
通讯作者:
Osbourn, Anne
DOI:
10.1073/pnas.0708242104
发表时间:
2007-10-16
影响因子:
11.1
作者:
Fujimori, Danica Galonic;Hrvatin, Sinisa;Walsh, Christopher T.
通讯作者:
Walsh, Christopher T.
影响因子:
7
作者:
Lee, JM;Sonnhammer, ELL
通讯作者:
Sonnhammer, ELL