The multiple time scales of sleep dynamics as a challenge for modelling the sleeping brain
The multiple time scales of sleep dynamics as a challenge for modelling the sleeping brain
复制标题
睡眠动态的多个时间尺度是对睡眠大脑建模的挑战
DOI：
10.1098/rsta.2011.0082
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
P. Achermann
中科院分区：
文献类型：
--
作者：
E. Olbrich;J. Claussen;P. Achermann
睡眠大脑的一个特殊性质是，它在非常不同的时间尺度上表现出动态，范围从典型的睡眠振荡，如睡眠纺锤波和慢波，可以在几秒钟的脑电(EEG)段中观察到，持续时间在分钟的不同睡眠阶段之间的转换，到涉及睡眠调节的动态过程，典型的时间常数在小时范围内。然而，处理这些不同动态的数学和计算模型的工作越来越多，通常只考虑单一时间尺度上的过程。在本文中，我们回顾和提出了一种新的分析人类睡眠脑电在不同时间尺度上的动力学，并将这些发现与最近的建模工作联系起来，指出了所取得的成就和仍然存在的挑战。
A particular property of the sleeping brain is that it exhibits dynamics on very different time scales ranging from the typical sleep oscillations such as sleep spindles and slow waves that can be observed in electroencephalogram (EEG) segments of several seconds duration over the transitions between the different sleep stages on a time scale of minutes to the dynamical processes involved in sleep regulation with typical time constants in the range of hours. There is an increasing body of work on mathematical and computational models addressing these different dynamics, however, usually considering only processes on a single time scale. In this paper, we review and present a new analysis of the dynamics of human sleep EEG at the different time scales and relate the findings to recent modelling efforts pointing out both the achievements and remaining challenges.
DOI：
10.1073/pnas.0408242101
发表时间：
2004-12-14
影响因子：
11.1
作者：
Lo, CC;Chou, T;Ivanov, PC
通讯作者：
Ivanov, PC