Physical activity and vascular comorbidity in Black and White persons with multiple sclerosis: A cross-sectional study.

Physical activity and vascular comorbidity in Black and White persons with multiple sclerosis: A cross-sectional study.
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DOI:
10.1016/j.dhjo.2022.101314
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发表时间:
2022-07
影响因子:
4.5
通讯作者:
Motl, Robert W.
Motl, Robert W.
中科院分区:
医学2区
文献类型:
--
作者:
Huynh, Trinh;Jeng, Brenda;Motl, Robert W.

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体力活动和久坐行为与多发性硬化症(MS)的血管合并症有关,但尚未在MS亚群中作为种族的函数对其相关性进行彻底研究。本研究检查了黑人和白色MS患者的体力活动水平/久坐时间和血管合并症是否存在差异,并进一步检查了两个MS亚群中变量之间的相关性。参与者(n=208)完成了MS合并症问卷,并佩戴加速度计7天,作为身体活动水平/久坐时间的设备测量。我们使用ANCOVA检查了种族对体力活动水平/久坐时间和血管共病的影响,控制了协变量。我们进一步进行了双变量之间的相关性,在黑人和白色人与MS分别。即使在控制了年龄、病程、婚姻状况、教育水平和收入后,黑人和白色MS患者之间只有中度至剧烈的体力活动(MVPA)存在显著差异[F(1,177)=9.01,p= 0.003,d=0.16]。在患有MS的白色人中,MVPA与血管合并症之间仅存在显著和中度相关性(r=-0.33)。研究结果表明,MVPA在白色人高于黑人MS患者,并且更多的MVPA与白色人MS患者的低血管合并症相关。体力活动行为可能是管理白色人MS患者血管合并症的潜在目标。
Physical activity and sedentary behavior have been associated with vascular comorbidity in multiple sclerosis (MS), yet the associations have not been thoroughly investigated in MS subpopulations as a function of race. This study examined if physical activity levels/sedentary time and vascular comorbidity differed between black and white persons with MS, and further examined the associations between the variables within the two MS subpopulations. Participants (n=208) completed the comorbidity questionnaire in MS and wore accelerometers for 7 days as a device-measure of physical activity levels/sedentary time. We examined the effect of race on physical activity levels/sedentary time and vascular comorbidity, controlling for covariates, using ANCOVA. We further performed bivariate correlations among variables in black and white persons with MS separately. Only moderate-to-vigorous physical activity (MVPA) was significantly different between black and white persons with MS, even after controlling for age, disease duration, marital status, education level, and income [F(1,177)=9.01, p=.003, d=0.16]. There was only a significant and moderate association between MVPA and vascular comorbidity in white persons with MS (r=−0.33). The findings indicate that MVPA is higher in white than black persons with MS, and that more MVPA was associated with lower vascular comorbidity in white persons with MS. Physical activity behavior might be a potential target for managing vascular comorbidity in white persons with MS.
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