Glutathione transferase GSTT1, broccoli, and prevalence of colorectal adenomas.
Glutathione transferase GSTT1, broccoli, and prevalence of colorectal adenomas.
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谷胱甘肽转移酶 GSTT1、西兰花和结直肠腺瘤的患病率。
DOI：
10.1097/00008571-200203000-00011
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Haile,RobertW
中科院分区：
文献类型：
--
作者：
Lin,HenryJ;Zhou,Haiyan;Dai,Aihua;Huang,Hsiao-Fen;Lin,JesseH;Frankl,HaroldD;Lee,EricR;Haile,RobertW
Vegetables in the mustard family (Cruciferae), such as broccoli, may prevent some cases of colorectal cancer [1±7]. These vegetables contain isothiocyanate compounds, which are pungent plant substances that have attracted attention since ancient times [8±10]. Approximately 100 plant isothiocyanates are known, but perhaps a dozen are important in widely eaten vegetables [11]. Sulforaphane, a broccoli isothiocyanate, is a potent inducer of carcinogen-detoxifying enzymes [12, 13], and it may also cause cell cycle arrest [14].Historically, enzymes that conjugate glutathione were prepared from rat liver [15]. Rat glutathione transferase E (GST 5±5) was found through its ability to open epoxide ring structures [16±18]. Around the same time, methyl chloride was shown to combine enzymatically with glutathione in human blood, with S-methylglutathione formed as a product [19]. However, methyl halide conjugating capacity in human red cells was polymorphic, with 20±40% of people thought to be non-conjugators [20±23].
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影响因子：
11.2
作者：
L. Gamet-Payrastre;Pengfei Li;S. Lumeau;G. Cassar;M. Dupont;S. Chevolleau;Nicole Gasc;J. Tulliez-J.-Tulli
通讯作者：
L. Gamet-Payrastre;Pengfei Li;S. Lumeau;G. Cassar;M. Dupont;S. Chevolleau;Nicole Gasc;J. Tulliez-J.-Tulli
食用抱子甘蓝对人体肠道和淋巴细胞谷胱甘肽 S-转移酶的影响。
影响因子：
4.7
作者：
W. Nijhoff;M.J.A.L. Grubben;F. Nagengast;Jan B.M.J. Jansen;Hans Verhagen;G. Poppel;Wilbert H.M. Peters
通讯作者：
Wilbert H.M. Peters
致癌物代谢的遗传多态性及其与遗传性非息肉性结肠癌的关联。
影响因子：
29.4
作者：
Moisio,AL;Sistonen,P;Mecklin,JP;Järvinen,H;Peltomäki,P
通讯作者：
Peltomäki,P
大鼠谷胱甘肽转移酶E的分离、性质及组织分布
影响因子：
3.5
作者：
D. Meyer;L. Christodoulides;K. Tan;B. Ketterer
通讯作者：
B. Ketterer
正常粘膜、移行粘膜和结直肠腺癌中谷胱甘肽S-转移酶T1和M1基因型
影响因子：
6.4
作者：
Hong Zhang;A. Ahmadi;G. Arbman;J. Zdolsek;J. Carstensen;B. Nordenskjöld;Peter Söderkvistand;Xiao Feng Sun
通讯作者：
Xiao Feng Sun