Novel Insights on Nitric Oxide Synthase and NO Signaling in Ascidian Metamorphosis.

Novel Insights on Nitric Oxide Synthase and NO Signaling in Ascidian Metamorphosis.
复制标题

关于一氧化氮合酶和NO信号在腹水变态中的新见解。

DOI:
10.3390/ijms23073505
复制
发表时间:
2022-03-23
影响因子:
5.6
通讯作者:
Palumbo A
Palumbo A
中科院分区:
生物学2区
文献类型:
--
作者:
Locascio A;Vassalli QA;Castellano I;Palumbo A

文献摘要

参考文献

被引文献

相似文献

一氧化氮(NO)是一种重要的信号分子,参与多种生理和病理过程。我们调查了NOS/NO定位模式在不同阶段的幼虫发育的海鞘海鞘粗壮,证明了一个特定的和时间控制的模式。NOS/NO的表达开始于早期幼虫的最前部的感觉结构,并随着幼虫的发育和变态进行逐渐向尾部移动。我们在这里强调的模式,NOS/NO的表达,在中枢和周围神经系统的玻璃海鞘幼虫,精确地遵循的进展所需的控制幼虫的运动向基板的中央模式发生器的神经信号。这种高度动态的本地化配置文件完全匹配的核心作用所发挥的NO从第一阶段的解决诱导到下一个控制的游泳行为,附着到基板和渐进的组织再吸收和重组的变态本身。
Nitric oxide (NO) is a pivotal signaling molecule involved in a wide range of physiological and pathological processes. We investigated NOS/NO localization patterns during the different stages of larval development in the ascidia Ciona robusta and evidenced a specific and temporally controlled pattern. NOS/NO expression starts in the most anterior sensory structures of the early larva and progressively moves towards the caudal portion as larval development and metamorphosis proceeds. We here highlight the pattern of NOS/NO expression in the central and peripheral nervous system of Ciona larvae which precisely follows the progression of neural signals of the central pattern generator necessary for the control of the movements of the larva towards the substrate. This highly dynamic localization profile perfectly matches with the central role played by NO from the first phase of settlement induction to the next control of swimming behavior, adhesion to substrate and progressive tissue resorption and reorganization of metamorphosis itself.
DOI: 10.1111/j.1460-9568.2005.04420.x
发表时间: 2005-11-01
影响因子: 3.4
作者:
Brown, ER;Nishino, A;Okamura, Y
通讯作者: Okamura, Y
DOI: 10.1038/s41598-017-08157-w
发表时间: 2017-08-16
期刊: Scientific reports
影响因子: 4.6
作者:
Annona G;Caccavale F;Pascual-Anaya J;Kuratani S;De Luca P;Palumbo A;D'Aniello S
通讯作者: D'Aniello S
DOI: 10.1371/journal.pone.0102907
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者:
Castellano I;Ercolesi E;Palumbo A
通讯作者: Palumbo A
DOI: 10.1152/jn.00283.2015
发表时间: 2016-03
影响因子: 2.5
作者:
Currie SP;Combes D;Scott NW;Simmers J;Sillar KT
通讯作者: Sillar KT
DOI: 10.1098/rsob.140182
发表时间: 2015-03
期刊: Open biology
影响因子: 5.8
作者:
Castellano I;Ercolesi E;Romano G;Ianora A;Palumbo A
通讯作者: Palumbo A