Comparison of 24-hour Holter monitoring with 14-day novel adhesive patch electrocardiographic monitoring.

Comparison of 24-hour Holter monitoring with 14-day novel adhesive patch electrocardiographic monitoring.
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DOI:
10.1016/j.amjmed.2013.10.003
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发表时间:
2014-01
影响因子:
5.9
通讯作者:
Topol, Eric J.
Topol, Eric J.
中科院分区:
医学2区
文献类型:
--
作者:
Barrett, Paddy M.;Komatireddy, Ravi;Haaser, Sharon;Topol, Sarah;Sheard, Judith;Encinas, Jackie;Fought, Angela J.;Topol, Eric J.

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心律失常非常常见,并且经常未被诊断,因为它们通常是短暂的且无症状。有效的诊断和治疗可以大大降低心律失常相关的发病率和死亡率。 Zio Patch(iRhythm Technologies, Inc,旧金山,加利福尼亚州)是一种新型、单导联心电图 (ECG)、轻型、美国食品和药物管理局批准的、连续记录的动态贴片监测仪,适用于检测转诊进行动态心电图监测的患者的心律失常。共有 146 名转诊进行心律失常评估的患者接受了使用传统 24 小时动态心电图监测仪和 14 天贴片监测仪的同步动态心电图记录。该研究的主要结果是比较两种设备在总佩戴时间内检测到的心律失常事件。心律失常事件定义为检测到 6 种心律失常中的任何一种,包括室上性心动过速、心房颤动/扑动、停顿超过 3 秒、房室传导阻滞、室性心动过速或多形性室性心动过速/心室颤动。麦克尼马尔的测试用于比较动态心电图和贴片监测仪的匹配数据对。在两种设备的总佩戴时间内,贴片监测仪检测到 96 例心律失常事件,而动态心电图监测仪检测到 61 例心律失常事件 (P < .001)。在两种设备的总佩戴时间内,贴片监测仪检测到的事件多于动态心电图监测仪。对于转诊进行动态心电图监测的患者,使用单导联、不那么引人注目的粘合贴片监测平台进行长时间监测以检测心律失常事件可以取代传统的动态心电图监测。
Cardiac arrhythmias are remarkably common and routinely go undiagnosed because they are often transient and asymptomatic. Effective diagnosis and treatment can substantially reduce the morbidity and mortality associated with cardiac arrhythmias. The Zio Patch (iRhythm Technologies, Inc, San Francisco, Calif) is a novel, single-lead electrocardiographic (ECG), lightweight, Food and Drug Administration–cleared, continuously recording ambulatory adhesive patch monitor suitable for detecting cardiac arrhythmias in patients referred for ambulatory ECG monitoring. A total of 146 patients referred for evaluation of cardiac arrhythmia underwent simultaneous ambulatory ECG recording with a conventional 24-hour Holter monitor and a 14-day adhesive patch monitor. The primary outcome of the study was to compare the detection arrhythmia events over total wear time for both devices. Arrhythmia events were defined as detection of any 1 of 6 arrhythmias, including supraventricular tachycardia, atrial fibrillation/flutter, pause greater than 3 seconds, atrioventricular block, ventricular tachycardia, or polymorphic ventricular tachycardia/ventricular fibrillation. McNemar’s tests were used to compare the matched pairs of data from the Holter and the adhesive patch monitor. Over the total wear time of both devices, the adhesive patch monitor detected 96 arrhythmia events compared with 61 arrhythmia events by the Holter monitor (P < .001). Over the total wear time of both devices, the adhesive patch monitor detected more events than the Holter monitor. Prolonged duration monitoring for detection of arrhythmia events using single-lead, less-obtrusive, adhesive-patch monitoring platforms could replace conventional Holter monitoring in patients referred for ambulatory ECG monitoring.
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