Spatial attention modulates center-surround interactions in macaque visual area v4.

Spatial attention modulates center-surround interactions in macaque visual area v4.
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DOI:
10.1016/j.neuron.2009.02.023
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发表时间:
2009-03-26
期刊:
影响因子:
16.2
通讯作者:
Reynolds, John H.
Reynolds, John H.
中科院分区:
医学1区
文献类型:
--
作者:
Sundberg, Kristy A.;Mitchell, Jude F.;Reynolds, John H.

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在自然观察中,作为注意目标的视觉刺激通常被许多无关的干扰物包围。落在感受野周围的刺激可以影响由出现在经典感受野内的刺激引起的神经元反应。这种任务无关的干扰物的调制可能会降低目标相关的神经元信号。因此,我们研究是否将注意力引导到目标刺激可以减少任务无关的干扰对神经元反应的影响。我们发现,在V4区注意到一个神经元的感受野内的刺激过滤掉了很大一部分的干扰出现在周围引起的抑制。当注意力被引导到周围刺激时,抑制增加,从而过滤掉对位于感受野内的不相关干扰物的神经元反应的一部分。这些发现表明,注意力调节引起中心-周围相互作用的神经机制。
In natural viewing a visual stimulus that is the target of attention is generally surrounded by many irrelevant distracters. Stimuli falling in the receptive field surround can influence the neuronal response evoked by a stimulus appearing within the classical receptive field. Such modulation by task-irrelevant distracters may degrade the target-related neuronal signal. We therefore examined whether directing attention to a target stimulus can reduce the influence of task-irrelevant distracters on neuronal response. We find that in area V4 attention to a stimulus within a neuron’s receptive field filters out a large fraction of the suppression induced by distracters appearing in the surround. When attention is instead directed to the surround stimulus suppression is increased, thereby filtering out part of the neuronal response to the irrelevant distracter positioned within the receptive field. These findings demonstrate that attention modulates the neural mechanisms that give rise to center-surround interactions.
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