Synthesis and nematicidal evaluation of 1,2,3-benzotriazin-4-one derivatives containing piperazine as linker against Meloidogyne incognita
Synthesis and nematicidal evaluation of 1,2,3-benzotriazin-4-one derivatives containing piperazine as linker against Meloidogyne incognita
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以哌嗪为连接体的1,2,3-苯并三嗪-4-酮衍生物的合成及杀线虫评价
DOI：
10.1016/j.cclet.2019.02.033
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发表时间：
2019-06
影响因子：
9.1
通讯作者：
Xu Xiaoyong
中科院分区：
文献类型：
--
作者：
Chen Xiulei;Jia Haowu;Li Zhong;Xu Xiaoyong
To explore new skeleton with nematicidal activity, a series of novel 1,2,3-benzotriazin-4-one derivatives containing piperazine as linker were synthesized and varied fragments were also introduced to increase structure diversity of the new skeleton. Their inhibitory activitiesin vivowere evaluated againstMeloidogyne incognita.The newly prepared compoundsA6, A8, A21, A28andA38exhibited more than 50% inhibition at the concentration of 20 mg/L. Especially compoundA6displayed 71.4% inhibition againstMeloidogyne incognitaat the concentration of 20 mg/L. The nematicidal activities varied significantly depending on the types and positions of the substituents, which provided guidance for further structure modification.
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