Initial evaluation of the Celesteion large-bore PET/CT scanner in accordance with the NEMA NU2-2012 standard and the Japanese guideline for oncology FDG PET/CT data acquisition protocol version 2.0.
Initial evaluation of the Celesteion large-bore PET/CT scanner in accordance with the NEMA NU2-2012 standard and the Japanese guideline for oncology FDG PET/CT data acquisition protocol version 2.0.
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DOI：
10.1186/s13550-017-0331-y
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发表时间：
2017-10-11
期刊：
影响因子：
3.2
通讯作者：
Inoue T
中科院分区：
文献类型：
--
作者：
Kaneta T;Ogawa M;Motomura N;Iizuka H;Arisawa T;Hino-Shishikura A;Yoshida K;Inoue T
本研究的目的是根据NEMA NU-2 2012标准和日本肿瘤学氟脱氧葡萄糖PET/CT数据采集方案指南第2.0版，评价Celesteion正电子发射断层扫描/计算机断层扫描（PET/CT）扫描仪的性能，其特征在于具有大口径和飞行时间（TOF）功能。根据NEMA NU-2 2012标准评价空间分辨率、灵敏度、计数率特性、散射分数、能量分辨率、TOF时间分辨率和图像质量。使用18F溶液和NEMA NU-2 2012标准中描述的IEC体模进行体模实验。根据日本指南计算了检测10 mm热球所需的最短扫描时间（目标与背景比为4：1）、体模噪声等效计数（NECphantom）、%背景变异性（N 10 mm）、%对比度（Q H，10 mm）和恢复系数（RC）。测量的空间分辨率范围从4.5 - 5毫米半高全宽（FWHM）。灵敏度和散射分数分别为3.8cps/kBq和37.3%。在体模中存在29.6 kBq mL − 1时，峰值噪声等效计数率为70 kcps。系统能量分辨率为12.4%，TOF时间分辨率为411 ps（FWHM）。根据日本指南，对于视觉评分、噪声等效计数（NEC）体模、N 10 mm和Q H、10 mm与N 10 mm比值（QNR），建议每个床位的最小扫描时间分别为2、7、6和2 min。直径为10 mm的球体的RC为0.49，超过了最小推荐值。与其他PET/CT扫描仪相比，Celesteion大口径PET/CT系统的灵敏度和NEC较低，但空间和时间分辨率良好。即使在2 min时，QNR也符合日本指南的推荐值。因此，认为Celesteion可提供可接受的图像质量，2分钟/床位采集，这是日本最常见的扫描方案。
The goal of this study was to evaluate the performance of the Celesteion positron emission tomography/computed tomography (PET/CT) scanner, which is characterized by a large-bore and time-of-flight (TOF) function, in accordance with the NEMA NU-2 2012 standard and version 2.0 of the Japanese guideline for oncology fluorodeoxyglucose PET/CT data acquisition protocol. Spatial resolution, sensitivity, count rate characteristic, scatter fraction, energy resolution, TOF timing resolution, and image quality were evaluated according to the NEMA NU-2 2012 standard. Phantom experiments were performed using 18F-solution and an IEC body phantom of the type described in the NEMA NU-2 2012 standard. The minimum scanning time required for the detection of a 10-mm hot sphere with a 4:1 target-to-background ratio, the phantom noise equivalent count (NECphantom), % background variability (N 10mm), % contrast (Q H,10mm), and recovery coefficient (RC) were calculated according to the Japanese guideline. The measured spatial resolution ranged from 4.5- to 5-mm full width at half maximum (FWHM). The sensitivity and scatter fraction were 3.8 cps/kBq and 37.3%, respectively. The peak noise-equivalent count rate was 70 kcps in the presence of 29.6 kBq mL−1 in the phantom. The system energy resolution was 12.4% and the TOF timing resolution was 411 ps at FWHM. Minimum scanning times of 2, 7, 6, and 2 min per bed position, respectively, are recommended for visual score, noise-equivalent count (NEC)phantom, N 10mm, and the Q H,10mm to N 10mm ratio (QNR) by the Japanese guideline. The RC of a 10-mm-diameter sphere was 0.49, which exceeded the minimum recommended value. The Celesteion large-bore PET/CT system had low sensitivity and NEC, but good spatial and time resolution when compared to other PET/CT scanners. The QNR met the recommended values of the Japanese guideline even at 2 min. The Celesteion is therefore thought to provide acceptable image quality with 2 min/bed position acquisition, which is the most common scan protocol in Japan.
影响因子：
1.8
作者：
Conti, Maurizio
通讯作者：
Conti, Maurizio
影响因子：
4
作者：
Rausch I;Cal-González J;Dapra D;Gallowitsch HJ;Lind P;Beyer T;Minear G
通讯作者：
Minear G
影响因子：
2.6
作者：
Fukukita, Hiroyoshi;Suzuki, Kazufumi;Matsumoto, Keiichi;Terauchi, Takashi;Daisaki, Hiromitsu;Ikari, Yasuhiko;Shimada, Naoki;Senda, Michio
通讯作者：
Senda, Michio