3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility.
3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility.
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DOI：
10.1038/s41598-018-31384-8
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发表时间：
2018-08-29
影响因子：
4.6
通讯作者：
Heiland S
中科院分区：
文献类型：
--
作者：
Juerchott A;Saleem MA;Hilgenfeld T;Freudlsperger C;Zingler S;Lux CJ;Bendszus M;Heiland S
本研究的目的是使用3 T高分辨率3D磁共振成像（MRI）验证基于标志的头影测量的几何准确性和体内重现性。对于准确度确认，在3个不同位置的体模上进行了96次角度和96次线性测量。对3名志愿者在5种头部位置进行体内MRI扫描。对于每次体内扫描，确定27个标志，从中计算19个角度和26个距离。采用Bland-Altman分析、双单侧检验程序和重复测量单因素方差分析进行统计学分析。与地面实况相比，所有基于MRI的体模测量结果均显示统计学等效性（p < 0.001），并且在Bland-Altman分析中具有极好的一致性（偏倚范围：−0.090-0.044°，−0.220-0.241 mm）。在所有研究参与者的五种不同头部位置中，体内头影测量分析具有高度可重复性，所有角度和距离均无统计学差异（p > 0.05）。体内最大值和最小值之间的范围始终分别小于2°和2 mm（平均范围：0.88°/0.87 mm）。总之，本研究表明，使用MRI可以在不暴露于电离辐射的情况下进行准确且可重现的3D头影测量分析。
The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. For accuracy validation, 96 angular and 96 linear measurements were taken on a phantom in 3 different positions. In vivo MRI scans were performed on 3 volunteers in five head positions. For each in vivo scan, 27 landmarks were determined from which 19 angles and 26 distances were calculated. Statistical analysis was performed using Bland-Altman analysis, the two one-sided tests procedure and repeated measures one-way analysis of variance. In comparison to ground truth, all MRI-based phantom measurements showed statistical equivalence (p < 0.001) and an excellent agreement in Bland-Altman analysis (bias ranges: −0.090–0.044°, −0.220–0.241 mm). In vivo cephalometric analysis was highly reproducible among the five different head positions in all study participants, without statistical differences for all angles and distances (p > 0.05). Ranges between maximum and minimum in vivo values were consistently smaller than 2° and 2 mm, respectively (average ranges: 0.88°/0.87 mm). In conclusion, this study demonstrates that accurate and reproducible 3D cephalometric analysis can be performed without exposure to ionizing radiation using MRI.
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作者：
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影响因子：
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DOI：
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发表时间：
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期刊：
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影响因子：
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作者：
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通讯作者：
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