Inducing chromosome pairing through premature condensation: analysis of wheat interspecific hybrids.

Inducing chromosome pairing through premature condensation: analysis of wheat interspecific hybrids.
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DOI:
10.1007/s10142-010-0185-0
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发表时间:
2010-11
影响因子:
2.9
通讯作者:
Moore, Graham
Moore, Graham
中科院分区:
生物学3区
文献类型:
--
作者:
Knight, Emilie;Greer, Emma;Draeger, Trade;Thole, Vera;Reader, Steve;Shaw, Peter;Moore, Graham

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在减数分裂开始时,染色体首先解密集,然后浓缩,因为同源染色体之间发生识别和亲密配对的过程。我们在这里表明,冈田酸,一种已知的诱导染色体凝聚的药物,可以引入到小麦种间杂种减数分裂前诱导染色体配对。这种配对发生在Ph 1基因座的存在下,这通常会抑制相关染色体的配对,我们在这里显示延迟凝聚。因此,减数分裂开始时染色体凝聚的时间是控制染色体配对的重要因素。本文的在线版本(doi:10.1007/s10142-010-0185-0)包含补充材料,可供授权用户使用。
At the onset of meiosis, chromosomes first decondense and then condense as the process of recognition and intimate pairing occurs between homologous chromosomes. We show here that okadaic acid, a drug known to induce chromosome condensation, can be introduced into wheat interspecific hybrids prior to meiosis to induce chromosome pairing. This pairing occurs in the presence of the Ph1 locus, which usually suppresses pairing of related chromosomes and which we show here delays condensation. Thus the timing of chromosome condensation during the onset of meiosis is an important factor in controlling chromosome pairing. The online version of this article (doi:10.1007/s10142-010-0185-0) contains supplementary material, which is available to authorized users.
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