The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011-2018.
The association between visceral adiposity index and chronic kidney disease in the elderly: A cross-sectional analysis of NHANES 2011-2018.
复制标题
老年人内脏肥胖指数与慢性肾脏疾病之间的关联：NHANES 2011-2018的横断面分析。
DOI：
10.1016/j.pmedr.2023.102306
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发表时间：
2023-10
影响因子：
2.8
通讯作者：
Xu, Gang
中科院分区：
文献类型：
--
作者：
Peng, Wei;Han, Min;Xu, Gang
在美国老年人群中，VAI与CKD风险显著相关。糖尿病对VAI与CKD的关系有显著影响。在老年人中，CKD的患病率随着VAI的增加而增加，VAI在0.5和5.0之间。内脏脂肪指数（VAI）是评价内脏脂肪功能障碍的新指标。本研究的目的是探讨美国老年人群中VAI与慢性肾脏病（CKD）事件之间的关系。我们纳入了6085名年龄在60岁或以上的参与者，这些参与者的肾功能和VAI数据来自2011年至2018年的国家健康和营养检查调查（NHANES），并根据VAI四分位数将他们分为四组。对VAI值进行ln转换以减少偏度。我们进行了多变量logistic回归分析和样条平滑图分析，以评估VAI和CKD之间的关联。在完全校正混杂因素后，较高的InVAI与较高的CKD风险相关（OR，1.23; 95%CI，1.02，1.48）。与Q1组（VAI < 1.1）相比，第三和第四VAI四分位数与较高的CKD患病率相关（Q3：VAI，1.8-3.0; Q4：VAI > 3.0）。Q3和Q4的校正OR（95% CI）分别为1.74（1.24，2.42）和1.59（1.08，2.33）。调整后的平滑图表明InVAI和CKD之间存在非线性关系。在InVAI介于-0.6至1.6之间（VAI：0.5-5.0）的参与者中，CKD的发展随着VAI的增加而增加。总之，VAI与美国60岁或以上老年人群的CKD风险显著相关。
VAI is significantly associated with the risk of CKD in the US elderly population. Diabetes has significant effect modification on the relationship between VAI and CKD. The prevalence of CKD increases with increasing VAI among the elderly with a VAI between 0.5 and 5.0. Visceral adiposity index (VAI) is a new metric for evaluating visceral adiposity dysfunction. The aim of the present study was to explore the association between VAI and incident chronic kidney disease (CKD) in the American elderly population. We included 6085 participants aged 60 years or older with available data on renal function and VAI from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2018 and divided them into four groups according to the VAI quartiles. VAI values were ln-transformed to reduce skewness. We conducted multivariable logistic regression analyses and spline smoothing plot analyses to evaluate the association between VAI and CKD. After fully adjusting for confounding factors, higher lnVAI was associated with a higher risk of CKD (OR, 1.23; 95 %CI, 1.02, 1.48). Compared to the Q1 group (VAI < 1.1), The third and fourth VAI quartiles were associated with a higher prevalence of CKD (Q3: VAI, 1.8–3.0; Q4: VAI > 3.0). The adjusted ORs (95% CI) in Q3 and Q4 were 1.74 (1.24, 2.42) and 1.59 (1.08, 2.33). Adjusted smoothed plots suggested a nonlinear relationship between lnVAI and CKD. The development of CKD increased with increasing VAI among participants with a lnVAI between −0.6 and 1.6 (VAI: 0.5–5.0). In conclusion, VAI is significantly associated with the risk of CKD in the US elderly population aged 60 years or older.
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影响因子：
5.2
作者：
Chen IJ;Hsu LT;Lu MC;Chen YJ;Tsou MT;Chen JY
通讯作者：
Chen JY
DOI：
10.1016/j.numecd.2017.06.015
发表时间：
2017-10-01
影响因子：
3.9
作者：
Kouli, G. -M.;Panagiotakos, D. B.;Pitsavos, C.
通讯作者：
Pitsavos, C.
影响因子：
8.3
作者：
Ellington, Allison A.;Malik, A. Rauoof;Kullo, Iftikhar J.
通讯作者：
Kullo, Iftikhar J.
影响因子：
6.1
作者：
Olivo, Robert E.;Davenport, Clemontina A.;Scialla, Julia J.
通讯作者：
Scialla, Julia J.
影响因子：
4.6
作者：
Barbieri, Diego;Goicoechea, Marian;Luno, Jose
通讯作者：
Luno, Jose