Lessons from simple marine models on the bacterial regulation of eukaryotic development.

Lessons from simple marine models on the bacterial regulation of eukaryotic development.
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DOI:
10.1016/j.mib.2017.12.013
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发表时间:
2018-06
影响因子:
5.4
通讯作者:
King N
King N
中科院分区:
生物学2区
文献类型:
--
作者:
Woznica A;King N

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来自环境细菌的分子线索影响着不同海洋真核生物的重要发育决定。然而,人们对这些相互作用背后的机制知之甚少,部分原因是海洋生态系统是动态和复杂的。在简单的模型系统的帮助下,包括有节鞭毛虫Salpingoeca Rosetta,我们已经开始揭示塑造海洋真核生物发展的细菌线索。在这里,我们回顾了不同的细菌信号--从脂类到大分子--如何调控海洋真核生物的发育。越来越清楚的是,海洋中存在着循环的化学信息网络,真核生物和细菌都充当节点;一个真核生物可以准确地响应来自几个不同环境细菌的信号,而一个环境细菌可以调节不同真核生物的发育。
Molecular cues from environmental bacteria influence important developmental decisions in diverse marine eukaryotes. Yet, relatively little is understood about the mechanisms underlying these interactions, in part because marine ecosystems are dynamic and complex. With the help of simple model systems, including the choanoflagellate Salpingoeca rosetta, we have begun to uncover the bacterial cues that shape eukaryotic development in the ocean. Here, we review how diverse bacterial cues — from lipids to macromolecules — regulate development in marine eukaryotes. It is becoming clear that there are networks of chemical information circulating in the ocean, with both eukaryotes and bacteria acting as nodes; one eukaryote can precisely respond to cues from several diverse environmental bacteria, and a single environmental bacterium can regulate the development of different eukaryotes.
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