Admission respiratory status predicts mortality in COVID-19.
Admission respiratory status predicts mortality in COVID-19.
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DOI:
10.1111/irv.12869
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发表时间:
2021-09
影响因子:
4.4
通讯作者:
Sotoodehnia N
中科院分区:
文献类型:
--
作者:
Chatterjee NA;Jensen PN;Harris AW;Nguyen DD;Huang HD;Cheng RK;Savla JJ;Larsen TR;Gomez JMD;Du-Fay-de-Lavallaz JM;Lemaitre RN;McKnight B;Gharib SA;Sotoodehnia N
COVID‐19 has significant case fatality. Glucocorticoids are the only treatment shown to improve survival, but only among patients requiring supplemental oxygen. WHO advises patients to seek medical care for “trouble breathing,” but hypoxemic patients frequently have no respiratory symptoms. Our cohort study of hospitalized COVID‐19 patients shows that respiratory symptoms are uncommon and not associated with mortality. By contrast, objective signs of respiratory compromise—oxygen saturation and respiratory rate—are associated with markedly elevated mortality. Our findings support expanding guidelines to include at‐home assessment of oxygen saturation and respiratory rate in order to expedite life‐saving treatments patients to high‐risk COVID‐19 patients.
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