The influences of walking, running and stair activity on knee articular cartilage: Quantitative MRI using T1 rho and T2 mapping.
The influences of walking, running and stair activity on knee articular cartilage: Quantitative MRI using T1 rho and T2 mapping.
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DOI：
10.1371/journal.pone.0187008
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Liu S
中科院分区：
文献类型：
--
作者：
Chen M;Qiu L;Shen S;Wang F;Zhang J;Zhang C;Liu S
利用T1 rho和T2图谱序列探讨步行、跑步和楼梯运动对膝关节软骨的不同影响。23名年轻健康成人分别在休息、散步、跑步和楼梯活动30分钟后立即进行右膝MRI （3.0-T）扫描。根据T1 rho和T2松弛时间定量评估关节软骨。采用随机区组设计数据的方差分析、bonferroni检验和配对样本t检验来估计生理活动对关节软骨的不同影响。关节软骨各区域生理活动后T1 rho和T2值均降低。T1 rho和T2值在跑步后比步行后下降更多。除了股骨软骨外，楼梯活动后T1 rho和T2值比跑步降低得更多。髌骨软骨浅层复位率高于深层复位率。关节软骨的T1 rho和T2值依次降低：髌股软骨>胫股内侧软骨>胫股外侧软骨。髌股软骨的复位顺序如下：外侧>中部>内侧。胫股软骨的复位顺序为：后部>中部>前部。T1 rho和T2作图序列可以定量反映生理活动对膝关节软骨的不同影响。流体位移、胶原纤维变形、空间异质性、材料性质的固有差异和组织刚度与软骨的载荷特性密切相关。
To explore the different influences of walking, running and stair activity on knee articular cartilage with T1 rho and T2 mapping sequences. MRI (3.0-T) scans of the right knee were performed in twenty-three young healthy adults immediately after 30 minutes of rest, walking, running and stair activity respectively. Articular cartilage was quantitatively assessed based on T1 rho and T2 relaxation times. Analysis of variance for random block design data, bonferroni test and paired samples t tests were performed to estimate the different influences of physiological activities on articular cartilage. T1 rho and T2 values had reductions after physiological activities in all regions of articular cartilage. T1 rho and T2 values were decreased more after running than walking. T1 rho and T2 values were decreased more after stair activity than running, except for femoral cartilage. The superficial layer of patella cartilage had higher reduction rates than the deep layer. The T1 rho and T2 values of articular cartilage were reduced in the following order: patellofemoral cartilage> medial tibiofemoral cartilage> lateral tibiofemoral cartilage. Patellofemoral cartilage experienced reductions in the following order: lateral part> middle part> medial part. Tibiofemoral cartilage had reductions in the following order: posterior part> middle part> anterior part. T1 rho and T2 mapping sequences can quantitatively reflect the different influences of physiological activities on knee articular cartilage. Fluid shifts, collagen fiber deformation, spatial heterogeneity, inherent differences in material properties and tissue stiffness have close relationship with cartilage loading characteristics.
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