Possible transmittance of A. actinomycetemcomitans from a dog to a child with rapidly destructive periodontitis.

Possible transmittance of A. actinomycetemcomitans from a dog to a child with rapidly destructive periodontitis.
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伴放线放线菌可能从狗传播给患有快速破坏性牙周炎的儿童。

DOI:
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发表时间:
1988
影响因子:
3.5
通讯作者:
Ingar Olsen
Ingar Olsen
中科院分区:
医学3区
文献类型:
--
作者:
H. Preus;Ingar Olsen

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本研究旨在检测口服A的可能外源性来源。在一个有2名儿童患有Papillon-Lefevre综合征(PLS)的家庭中发现伴放线菌。每个月1年龈下牙菌斑样本从2个孩子,他们的父母,祖父母和他们的宠物狗。牙菌斑样本也从一个12岁的男孩,他的家庭拥有一只狗从同一窝PLS家庭。将分散和稀释的噬菌斑样品在Slots培养基和A.根据标准标准鉴定伴放线菌。不同的A.大量培养伴放线菌野生菌株,用ECO RI、HIND III和BAM HI在2种不同的电泳凝胶上进行DNA限制性内切酶图谱分析后,比较它们的总基因组。仅来自PLS儿童、宠物狗和12岁男孩中的1个的牙菌斑样品产生A。伴放线菌限制性内切酶不能区分A.来自PLS儿童的伴放线菌野生菌株和来自家庭狗或12岁男孩的菌株。然而,该方法可以很容易地区分参考菌株和野生菌株,表明A。从狗到PLS儿童都发生了伴放线菌感染。
This study was designed to detect a possible exogenous source of oral A. actinomycetemcomitans in a family where the 2 children suffered from Papillon-Lefevre syndrome (PLS). Every month for 1 yr subgingival dental plaque samples were obtained from the 2 children, their parents, grandparents and their pet dog. Dental plaque samples were also obtained from a 12-yr-old boy whose family had owned a dog from the same litter as the PLS family. Dispersed and diluted plaque samples were cultured anaerobically on Slots medium and A. actinomycetemcomitans was identified by standard criteria. The various A. actinomycetemcomitans wild strains were mass cultivated and their total genomes compared after DNA restriction endonuclease mapping in 2 different electrophoretic gels, using ECO RI, HIND III and BAM HI. Only the plaque samples from 1 of the PLS children, the pet dog and the 12-yr-old boy produced A. actinomycetemcomitans. The restriction endonucleases could not distinguish between the A. actinomycetemcomitans wild strains from the PLS child and those from the family dog or the 12-yr-old boy. However, the methods could readily differentiate between both reference strains and wild strains, indicating that transfer of A. actinomycetemcomitans from dog to the PLS child had taken place.
DOI: 10.1902/jop.1983.54.12.707
发表时间: 1983
影响因子: 4.3
作者:
Zambon,JJ;Christersson,LA;Slots,J
通讯作者: Slots,J
DOI: 10.1056/nejm198207013070101
发表时间: 1982
期刊: The New England journal of medicine
影响因子: --
作者:
O'Brien,TF;Hopkins,JD;Gilleece,ES;Medeiros,AA;Kent,RL;Blackburn,BO;Holmes,MB;Reardon,JP;Vergeront,JM;Schell,WL;Christenson,E;Bissett,ML;Morse,EV
通讯作者: Morse,EV
DOI: 10.1902/jop.1985.56.3.127
发表时间: 1985-01-01
影响因子: 4.3
作者:
CHRISTERSSON, LA;SLOTS, J;GENCO, RJ
通讯作者: GENCO, RJ