The Diagnostic Value of Global Longitudinal Strain (GLS) on Myocardial Infarction Size by Echocardiography: A Systematic Review and Meta-analysis.
The Diagnostic Value of Global Longitudinal Strain (GLS) on Myocardial Infarction Size by Echocardiography: A Systematic Review and Meta-analysis.
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超声心动图整体纵向应变（GLS）对心肌梗死大小的诊断价值：系统评价和荟萃分析
DOI：
10.1038/s41598-017-09096-2
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发表时间：
2017-08-30
影响因子：
4.6
通讯作者：
Guo YK
中科院分区：
文献类型：
--
作者：
Diao KY;Yang ZG;Ma M;He Y;Zhao Q;Liu X;Gao Y;Xie LJ;Guo YK
我们对前瞻性随机研究进行了系统回顾和荟萃分析，以评估使用斑点跟踪超声心动图（STE）测量总体纵向应变（GLS）在确定心肌梗死（MI）大小中的诊断价值，心肌梗死（MI）大小通常是基于心血管磁共振（CMR）晚期钆增强（LGE）测量的。11项试验共纳入765例患者。二维（2D） GLS与LGE百分比的总相关性为0.70 (95% CI: 0.64, 0.74)，三维（3D） GLS的总相关性为0.55 （95% CI: 0.19, 0.78）。2D GLS鉴别心肌梗死大小的综合诊断估计如下：敏感性0.77 (95% CI: 0.61, 0.90)；特异性为0.86 (95% CI: 0.68, 0.96)；阳性似然比（PLR）， 8.13 (95% CI: 1.90, 26.61)；负似然比（NLR）， 0.28 (95% CI: 0.10, 0.54)；诊断优势比（DOR）为39.87 （95% CI: 4.12, 172.83）。综合受试者工作特征（SROC）曲线下面积（AUC）估计为0.702。对于首次心肌梗死患者，2D STE结果与CMR量化的梗死面积呈正相关，可作为评估梗死面积的良好诊断指标。然而，仍然需要更多的综合STE研究来确定3D STE的价值。
A systematic review and meta-analysis of prospective randomized studies were performed to evaluate the diagnostic value of measuring global longitudinal strain (GLS) using speckle tracking echocardiography (STE) in determining myocardial infarction (MI) size, which is usually measured based on late gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR). Eleven trials with a total of 765 patients were included. The pooled correlation was 0.70 (95% CI: 0.64, 0.74) between two-dimensional (2D) GLS and the LGE percentage, and it was 0.55 (95% CI: 0.19, 0.78) for three-dimensional (3D) GLS. Pooled diagnostic estimates for 2D GLS to differentiate an MI size >12% were as follows: sensitivity, 0.77 (95% CI: 0.61, 0.90); specificity, 0.86 (95% CI: 0.68, 0.96); positive likelihood ratio (PLR), 8.13 (95% CI: 1.90, 26.61); negative likelihood ratio (NLR), 0.28 (95% CI: 0.10, 0.54); and diagnostic odds ratio (DOR), 39.87 (95% CI: 4.12, 172.83). The estimated area under the curve (AUC) of the summary receiver operating characteristic (SROC) curve was 0.702. The 2D STE results positively correlated with the infarction size quantified by CMR for patients who had experienced their first MI. This approach can serve as a good diagnostic index for assessing infarction area. However, more consolidated STE studies are still needed to determine the value of 3D STE.
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影响因子：
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作者：
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作者：
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DOI：
10.1186/s12968-016-0313-7
发表时间：
2016-12-12
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Diao KY;Yang ZG;Xu HY;Liu X;Zhang Q;Shi K;Jiang L;Xie LJ;Wen LY;Guo YK
通讯作者：
Guo YK