miRNAs in synapse development and synaptic plasticity.
miRNAs in synapse development and synaptic plasticity.
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DOI：
10.1016/j.conb.2017.02.014
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发表时间：
2017-08
影响因子：
5.7
通讯作者：
Li Z
中科院分区：
文献类型：
--
作者：
Hu Z;Li Z
Synapses are functional units of the nervous system, through which information is transferred between neurons. The development and activity-dependent modification of synapses require temporally and spatially controlled modulation of gene expression. microRNAs (miRNAs) have emerged as essential regulators of gene expression. They are small non-coding RNAs that regulate mRNA stability and translation by interacting with the 3′ untranslated region (3′ UTR) of mRNAs. miRNAs are located to neuronal processes to regulate protein synthesis locally and their expression is regulated by synaptic activity. This article reviews recent findings on the role of miRNAs in synapse development and synaptic plasticity.
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影响因子：
16.2
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DOI：
10.1523/jneurosci.1312-12.2012
发表时间：
2012-10-10
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
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