IFCN-endorsed practical guidelines for clinical magnetoencephalography (MEG).
IFCN-endorsed practical guidelines for clinical magnetoencephalography (MEG).
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DOI：
10.1016/j.clinph.2018.03.042
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发表时间：
2018-08
期刊：
影响因子：
--
通讯作者：
Taulu S
中科院分区：
文献类型：
--
作者：
Hari R;Baillet S;Barnes G;Burgess R;Forss N;Gross J;Hämäläinen M;Jensen O;Kakigi R;Mauguière F;Nakasato N;Puce A;Romani GL;Schnitzler A;Taulu S
本文讨论了脑磁图（MEG）的基本原理及MEG与EEG联合应用的价值。本文综述了脑磁图的临床应用。临床脑磁图检查的实用指南。脑磁图（MEG）记录人头部外的弱磁场，从而提供有关支持人脑功能的神经元电流的毫秒级精确信息。MEG和脑电图（EEG）是密切相关的互补方法，应尽可能一起解释。这份手稿涵盖了MEG的基本物理和生理原理，并讨论了最先进的MEG数据分析的主要方面。我们为患者准备、刺激呈现、MEG数据收集和分析以及常规临床检查中的MEG解读提供最佳实践指南。2017年，全球约有200台全头皮MEG设备在运行，其中许多位于临床环境中。然而，MEG检查的临床适应症仍然很少，主要限于癫痫的诊断和神经外科患者的术前功能评估。我们相信，正在进行的广泛的基础脑磁图研究表明，有潜力的神经和精神综合征，发育障碍，脑卒中后皮质脑网络的完整性进行评估。因此，基础和临床研究为越来越多的MEG从业者确定新的临床应用铺平了道路。
The main principles of magnetoencephalography (MEG) and the value of combined MEG and EEG are discussed. Established and some potential future clinical applications of MEG are reviewed. Practical guidelines for clinical MEG examinations are presented. Magnetoencephalography (MEG) records weak magnetic fields outside the human head and thereby provides millisecond-accurate information about neuronal currents supporting human brain function. MEG and electroencephalography (EEG) are closely related complementary methods and should be interpreted together whenever possible. This manuscript covers the basic physical and physiological principles of MEG and discusses the main aspects of state-of-the-art MEG data analysis. We provide guidelines for best practices of patient preparation, stimulus presentation, MEG data collection and analysis, as well as for MEG interpretation in routine clinical examinations. In 2017, about 200 whole-scalp MEG devices were in operation worldwide, many of them located in clinical environments. Yet, the established clinical indications for MEG examinations remain few, mainly restricted to the diagnostics of epilepsy and to preoperative functional evaluation of neurosurgical patients. We are confident that the extensive ongoing basic MEG research indicates potential for the evaluation of neurological and psychiatric syndromes, developmental disorders, and the integrity of cortical brain networks after stroke. Basic and clinical research is, thus, paving way for new clinical applications to be identified by an increasing number of practitioners of MEG.
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