Aspergillus niger as a Secondary Metabolite Factory.
Aspergillus niger as a Secondary Metabolite Factory.
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DOI:
10.3389/fchem.2021.701022
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发表时间:
2021
影响因子:
5.5
通讯作者:
Zhang H
中科院分区:
文献类型:
--
作者:
Yu R;Liu J;Wang Y;Wang H;Zhang H
Aspergillus niger, one of the most common and important fungal species, is ubiquitous in various environments. A. niger isolates possess a large number of cryptic biosynthetic gene clusters (BGCs) and produce various biomolecules as secondary metabolites with a broad spectrum of application fields covering agriculture, food, and pharmaceutical industry. By extensive literature search, this review with a comprehensive summary on biological and chemical aspects of A. niger strains including their sources, BGCs, and secondary metabolites as well as biological properties and biosynthetic pathways is presented. Future perspectives on the discovery of more A. niger-derived functional biomolecules are also provided in this review.
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