Bone Mechanical Properties in Healthy and Diseased States.
Bone Mechanical Properties in Healthy and Diseased States.
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DOI:
10.1146/annurev-bioeng-062117-121139
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发表时间:
2018-06-04
影响因子:
9.7
通讯作者:
Hussein AI
中科院分区:
文献类型:
--
作者:
Morgan EF;Unnikrisnan GU;Hussein AI
The mechanical properties of bone are fundamental to the ability of our skeletons to support movement and to provide protection to our vital organs. As such, deterioration in mechanical behavior with aging and/or diseases such as osteoporosis and diabetes can have profound consequences for individuals’ quality of life. This article reviews current knowledge of the basic mechanical behavior of bone at length scales ranging from hundreds of nanometers to tens of centimeters. We present the basic tenets of bone mechanics and connect them to some of the arcs of research that have brought the field to recent advances. We also discuss cortical bone, trabecular bone, and whole bones, as well as multiple aspects of material behavior, including elasticity, yield, fracture, fatigue, and damage. We describe the roles of bone quantity (e.g., density, porosity) and bone quality (e.g., cross-linking, protein composition), along with several avenues of future research.
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影响因子:
2.4
作者:
Bigley, Robert F.;Griffin, Lanny V.;Vandenbosch, Ryan
通讯作者:
Vandenbosch, Ryan
影响因子:
2.4
作者:
Bevill, Grant;Farhamand, Farhad;Keaveny, Tony M.
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Keaveny, Tony M.
DOI:
10.2106/00004623-197658010-00015
发表时间:
1976-01-01
影响因子:
5.3
作者:
BURSTEIN, AH;REILLY, DT;MARTENS, M
通讯作者:
MARTENS, M
DOI:
10.1016/s0020-7683(98)00338-2
发表时间:
2000-05-01
影响因子:
3.6
作者:
Arramon, YP;Mehrabadi, MM;Cowin, SC
通讯作者:
Cowin, SC
DOI:
10.1359/jbmr.080517
发表时间:
2008-10
期刊:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
影响因子:
--
作者:
Arlot ME;Burt-Pichat B;Roux JP;Vashishth D;Bouxsein ML;Delmas PD
通讯作者:
Delmas PD