Questionnaire assessments of recent exposure to environmental tobacco smoke in relation to salivary cotinine.
Questionnaire assessments of recent exposure to environmental tobacco smoke in relation to salivary cotinine.
复制标题
对最近接触环境烟草烟雾与唾液可替宁的关系进行问卷评估。
DOI：
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发表时间：
1993
影响因子：
24.3
通讯作者：
M. R. Becklake
中科院分区：
文献类型：
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作者：
R. Delfino;Pierre Ernst;M. Jaakkola;Scott D. Solomon;M. R. Becklake
越来越多的证据表明环境烟草烟雾 (ETS) 对健康造成不良影响，这促使人们寻找准确的 ETS 暴露测量方法。本研究探讨是否有可能增强基于问卷的 ETS 暴露评估的能力，以预测唾液可替宁。唾液样本取自 258 名不吸烟的银行员工，他们同时回答了详细说明过去三天内接触二手烟的问题。创建暴露模型时考虑了附近吸烟者的数量、吸烟者存在的时间长度、体液中可替宁的半衰期、对香烟烟雾的厌恶程度以及一年中的时间。所有模型，包括综合考虑暴露强度和持续时间，都解释了对数可替宁水平的等量方差（约 16%）。本研究发现，ETS 暴露的问卷估计值与可替宁之间的弱关系表明，需要进一步调查以改进对近期 ETS 暴露的评估。
The increasing evidence of the ill-health effects of environmental tobacco smoke (ETS) has prompted the search for accurate measures of exposure to ETS. The present study examined whether it was possible to enhance the ability of questionnaire-derived assessments of ETS exposure, to predict salivary cotinine. Salivary samples were obtained from 258 nonsmoking bank employees, who simultaneously answered questions detailing their exposure to second-hand smoke within the last three days. Exposure models were created, to take into account the number of smokers nearby, length of time in their presence, half-life of cotinine in bodily fluids, level of aversion to cigarette smoke and time of year. All models, including the consideration of intensity and duration of exposure combined, explained an equal amount of variance of log cotinine levels (approximately 16%). The weak relationship between questionnaire estimates of ETS exposure and cotinine, found in the present study, suggests that further investigation is needed to improve the assessment of recent ETS exposure.
自我报告的环境烟草烟雾暴露的生化验证。
影响因子：
8.3
作者：
Haley,NJ;Colosimo,SG;Axelrad,CM;Harris,R;Sepkovic,DW
通讯作者：
Sepkovic,DW