Responsive Vagus Nerve Stimulation for Drug Resistant Epilepsy: A Review of New Features and Practical Guidance for Advanced Practice Providers.
Responsive Vagus Nerve Stimulation for Drug Resistant Epilepsy: A Review of New Features and Practical Guidance for Advanced Practice Providers.
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DOI：
10.3389/fneur.2020.610379
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发表时间：
2020
影响因子：
3.4
通讯作者：
Melamed SE
中科院分区：
文献类型：
--
作者：
Fisher B;DesMarteau JA;Koontz EH;Wilks SJ;Melamed SE
迷走神经刺激（VNS）是一种安全有效的治疗方法，已用于成人和儿童耐药性癫痫（DRE）治疗超过20年。自1997年美国食品和药物管理局批准以来，VNS已被植入超过100，000名患者，包括超过30，000名儿童，作为减少4岁及以上患有抗癫痫药物难治性局灶性癫痫发作的患者癫痫发作频率的连续治疗。VNS Therapy®随着时间的推移而发展，目前提供闭环响应刺激以及简化给药和患者管理的高级功能。高级实践提供者（APP），如执业护士，医生助理和临床护士专家是综合医疗团队的组成部分，专门的VNS诊所已在世界各地的综合癫痫中心形成，这些中心通常由APP管理。这种方法改善了VNS患者或正在考虑VNS的人获得护理的机会、教育和连续性。在此，我们对VNS Therapy®系统上的APP进行了综述，重点关注新功能、剂量和故障排除策略，旨在为管理VNS患者的人员提供指导。
Vagus nerve stimulation (VNS) is a safe and effective therapy that has been available for over 20 years for adults and children with drug resistant epilepsy (DRE). Since U.S. Food and Drug Administration approval in 1997, VNS has been implanted in over 100,000 patients including over 30,000 children as an adjunctive therapy in reducing the frequency of seizures in patients 4 years of age and older with focal seizures that are refractory to antiseizure medications. VNS Therapy® has evolved over time and currently offers closed-loop, responsive stimulation as well as advanced features that streamline dosing and patient management. Advanced Practice Providers (APPs) such as nurse practitioners, physician assistants and clinical nurse specialists are integral in a comprehensive healthcare team, and dedicated VNS clinics have formed at comprehensive epilepsy centers across the world that are often managed by APPs. This approach improves access, education, and continuity of care for those with VNS or those considering VNS. Here we provide a review for APPs on the VNS Therapy® system focused on new features, dosing, and troubleshooting strategies with the goal to provide guidance to those managing VNS patients.
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