Clinical characteristics of non-intensive care unit COVID-19 patients in Saudi Arabia: A descriptive cross-sectional study.
Clinical characteristics of non-intensive care unit COVID-19 patients in Saudi Arabia: A descriptive cross-sectional study.
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DOI：
10.1016/j.jiph.2020.09.003
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发表时间：
2020-11
影响因子：
6.7
通讯作者：
Al Mutair A
中科院分区：
文献类型：
--
作者：
Al-Omari A;Alhuqbani WN;Zaidi ARZ;Al-Subaie MF;AlHindi AM;Abogosh AK;Alrasheed AK;Alsharafi AA;Alhuqbani MN;Salih S;Alhedaithy MA;Abdulqawi R;Ismail AF;Alhumaid S;Hamdan N;Saad F;Olhaye FA;Eltahir TA;Alomari M;Alshehery M;Yassiri A;Al-Tawfiq JA;Al Mutair A
正在流行的2019冠状病毒病（COVID-19）是一个全球卫生问题。它影响了全世界500多万患者，并在全球造成了惊人的死亡人数。虽然其他地方已经报道了临床特征，但我们地区的数据很少。我们调查了沙特阿拉伯轻至中度COVID-19病例的临床特征。这是一项描述性的横断面研究。2020年4月22日至2020年5月21日，在沙特阿拉伯利雅得的五家三级医院收集了401名COVID-19确诊患者的数据。患者按年龄分为4组，1组0 ~ <18岁，2组18 ~ <50岁，3组50 ~ 60岁，4组60 ~ 60岁；比较两组患者的临床症状。I组的中位（IQR）年龄为10.5（1.5 - 16）岁，II组为34（29 - 41）岁，III组为53（51 - 56）岁，IV组为66（61 - 76）岁。大多数患者为男性（80%,n = 322），阿拉伯或亚洲血统。住院时间中位数为10（8-17）天（范围3-42天）。最常见的症状是咳嗽（53.6%）、发烧（36.2%）、疲劳（26.4%）、呼吸困难（21.9%）和喉咙痛（21.9%）。高血压是最常见的潜在合并症（14.7%），其次是肥胖（11.5%）和糖尿病（10%）。高血压患者较少出现呼吸短促、咳嗽、咳痰、腹泻和发烧。不同年龄组间症状差异无统计学意义，合并症以老年组多见。有趣的是，高血压患者的症状较轻，住院时间较短。需要进一步开展更大规模的国家合作研究，以有效了解我们这一地区的临床特征，从而有效地管理和控制SARS-CoV-2的传播。
The ongoing pandemic of the coronavirus disease 2019 (COVID-19) is a global health concern. It has affected more than 5 million patients worldwide and resulted in an alarming number of deaths globally. While clinical characteristics have been reported elsewhere, data from our region is scarce. We investigated the clinical characteristics of mild to moderate cases of COVID-19 in Saudi Arabia. This is a descriptive, cross-sectional study. Data of 401 confirmed COVID-19 patients were collected from 22 April 2020 to 21 May 2020 at five tertiary care hospitals in Riyadh, Saudi Arabia. The patients were divided into four groups according to age, Group 1: 0–<18 years, Group 2: 18–<50 years, Group 3: 50–60 years, and Group 4: >60 years; and their clinical symptoms were compared. The median (IQR) age in years was 10.5 (1.5−16) in group I, 34 (29−41) in group II, 53 (51−56) in group III, and 66 (61−76) in group IV. Most patients were male (80%, n = 322) and of Arabian or Asian descent. The median length of stay in the hospital was 10 (8–17) days (range 3–42 days). The most common symptoms were cough (53.6%), fever (36.2%), fatigue (26.4%), dyspnea (21.9%), and sore throat (21.9%). Hypertension was the most common underlying comorbidity (14.7%), followed by obesity (11.5%), and diabetes (10%). Hypertensive patients were less likely to present with shortness of breath, cough, sputum, diarrhea, and fever. There was no significant difference in the symptoms among different age groups and comorbidities were mostly seen in the older age group. Interestingly, hypertensive patients were found to have milder symptoms and a shorter length of stay. Further larger collaborative national studies are required to effectively understand clinical characteristics in our part of the world to efficiently manage and control the spread of SARS-CoV-2.
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DOI：
10.4049/jimmunol.1601896
发表时间：
2017-05-15
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Channappanavar R;Fett C;Mack M;Ten Eyck PP;Meyerholz DK;Perlman S
通讯作者：
Perlman S
DOI：
10.1164/rccm.202002-0445oc
发表时间：
2020-06-01
影响因子：
24.7
作者：
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通讯作者：
Qu, Jieming
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin
影响因子：
10
作者：
Chan, JWM;Ng, CK;Li, PCK
通讯作者：
Li, PCK
轻度疾病严重程度的 COVID-19 患者的消化道症状：临床表现、粪便病毒 RNA 检测和结果
影响因子：
9.8
作者：
Han, Chaoqun;Duan, Caihan;Hou, Xiaohua
通讯作者：
Hou, Xiaohua