Prospective surveillance of invasive group a streptococcal disease, Fiji, 2005-2007.
Prospective surveillance of invasive group a streptococcal disease, Fiji, 2005-2007.
复制标题
DOI：
10.3201/eid1502.080558
复制
发表时间：
2009-02
影响因子：
11.8
通讯作者：
Carapetis JR
中科院分区：
文献类型：
--
作者：
Steer AC;Jenney A;Kado J;Good MF;Batzloff M;Waqatakirewa L;Mullholland EK;Carapetis JR
这些感染在斐济比在工业化国家更常见，病死率也更高。2005-2007年，我们对斐济的侵袭性A组链球菌病进行了为期23个月的前瞻性积极监测研究。我们确定了64例侵袭性GAS疾病，这代表了平均每年9.9例/100，000人群（95%置信区间[CI] 7.6-12.6）。年龄>65岁和<5岁的患者发病率最高，尤其是婴儿，其发病率为44.9/100，000（95%CI 18.1-92.5）。病死率为32%，与年龄增长和基础并存疾病（包括糖尿病和肾脏疾病）有关。55个GAS分离株进行了emm序列分型;类型高度多样，有38种不同的emm亚型，没有特定的优势类型。我们的数据支持这样的观点，即侵袭性GAS疾病在发展中国家很常见，应该得到更多的公共卫生关注。
These infections are more common and case-fatality rate is higher in Fiji than in industrialized countries. We undertook a prospective active surveillance study of invasive group A streptococcal (GAS) disease in Fiji over a 23-month period, 2005–2007. We identified 64 cases of invasive GAS disease, which represents an average annualized all-ages incidence of 9.9 cases/100,000 population per year (95% confidence interval [CI] 7.6–12.6). Rates were highest in those >65 years of age and in those <5 years, particularly in infants, for whom the incidence was 44.9/100,000 (95% CI 18.1–92.5). The case-fatality rate was 32% and was associated with increasing age and underlying coexisting disease, including diabetes and renal disease. Fifty-five of the GAS isolates underwent emm sequence typing; the types were highly diverse, with 38 different emm subtypes and no particular dominant type. Our data support the view that invasive GAS disease is common in developing countries and deserves increased public health attention.
登录
查看更多内容
DOI：
10.1517/17530059.2.3.289
发表时间：
2008-03-01
期刊：
Expert opinion on medical diagnostics
影响因子：
--
作者：
Steer, Andrew C;Curtis, Nigel;Carapetis, Jonathan R
通讯作者：
Carapetis, Jonathan R
影响因子：
6.4
作者：
Li, ZY;Sakota, V;Beall, B
通讯作者：
Beall, B
影响因子：
11.8
作者：
Bisno, AL;Rubin, FA;Dale, JB
通讯作者：
Dale, JB
影响因子：
11.8
作者：
O'Loughlin, Rosalyn E.;Roberson, Angela;Van Beneden, Chris
通讯作者：
Van Beneden, Chris
影响因子：
158.5
作者：
Berkley, JA;Lowe, BS;Scott, JAG
通讯作者：
Scott, JAG